Searchable abstracts of presentations at key conferences in endocrinology

ea0028p180 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2012

Circadian dietary rhythms: association with the metabolic syndrome in the 1946 British birth cohort

Almoosawi Suzana , Prynne Celia , Hardy Rebecca , Lennox Alison

Epidemiological evidence suggests that timing of eating and nutrient composition of meals can predict obesity development. However, few studies have examined the association between nutrient composition of eating occasions and prevalence of metabolic syndrome. We examined the association between time-of-day and nutrient composition of eating occasions and long-term development of metabolic syndrome in the MRC National Survey of Health and Development (1946 British birth cohort...

ea0020p470 | Obesity and Metabolism | ECE2009

Effects of green tea consumption on blood pressure, total cholesterol, body weight and fat in healthy volunteers

Al-Dujaili Emad , Bradley Jon-Paul , Almoosawi Suzana , Fyfe Lorna

Background: Hypertension, obesity and hyperlipidemia are key interlinked features of both metabolic syndrome and cardiovascular disease. Numerous studies have suggested that green tea may reduce blood pressure by activating endothelial nitric oxide synthase and reducing total cholesterol by disrupting the production of apo B and synthesis of chylomicrons and thus have cardio-protective effects. The aim of this pilot study was to investigate the effects of increasing the consum...

ea0021p343 | Steroids | SFEBES2009

Application of a highly specific and sensitive ELISA for the estimation of cortisone in biological fluids

Baghdadi Hussam , Al-Dujaili Emad , Almoosawi Suzana , Howie Forbes , Mason Ian

It is now generally acknowledged that local tissue concentrations of cortisol and cortisone are modulated by site-specific actions of 11β-hydroxysteroid dehydrogenase (11β-HSD) isoenzymes 1 and 2. Cortisone, the inactive metabolite of cortisol is produced by type 2 11β-HSD. To assess 11β-HSD type 1 and 2 activity, the cortisone/cortisol ratio has to be accurately determined. Immunoassays to measure cortisone levels are not widely available and tend to lack ...