Searchable abstracts of presentations at key conferences in endocrinology

ea0082p7 | Poster Presentations | SFEEU2022

Widespread skin hypopigmentation caused by finasteride when used for female hirsutism

Bawden David , Stratos Efstratios , Swe Myint Khin

Case history: A 39 year old lady was referred to endocrinology with hirsutism. In the clinic, the pattern of hair growth was confirmed as androgenic, she had cliteromegaly and family members had commented on her voice deepening. She underwent menarche at 13 years old, has menorrhagia and has had hirsutism her entire adult life that had recently worsened. Her biochemistry confirmed hyperandrogenism with non-suppressed LH/FSH. At her second appointment after serious pathology ha...

ea0031p344 | Steroids | SFEBES2013

Feature of acute mineralocorticoid excess from ACTH secreting bronchial tumour

Seidahmad Mansour , Haddadin Firas , Swe Myint Khin

Introduction: A 77-year-old man with glipizide treated type 2 diabetes presented acutely unwell, with weakness, intermittent breathlessness, and poor glycaemic control (previously well control with HBA1c of 42 mmol/mol). Initial assessment showed body weight of 74.5 kg, mild leg oedema, blood pressure of 190/100 mmHg, expiratory wheeze, oxygen saturation 91% and PO2 7.8 mmHg on air. Chest XR showed chronic right lower lobe shadowing and a bulky hilum. His plasma glu...

ea0086p23 | Adrenal and Cardiovascular | SFEBES2022

Endocrine Complications and Metabolic Risk in Sleep Apnoea

Bawden David , Stratos Efstratios , Cordell Christopher , Swe Myint Khin

Introduction: Within our single centre, the referral rate from the endocrine hypertension clinic to the sleep clinic is high. We have also observed a particular metabolic profile of those patients including raised normetanephrines which subsequently improve after treatment for sleep apnoea.Illustrative cases: 56 year old man with a BMI of 33 kg/m2 and multiple complications of obesity including NAFLD, gallstones and loss of libido. He was rare...

ea0086p196 | Endocrine Cancer and Late Effects | SFEBES2022

Prevalence of vitamin B12 deficiency in neuroendocrine tumour-Single Centre Experience

Tun Yee LaiLai , Myint Han Myint , Kapur Gaurav , Swe Myint Khin

Background: Neuroendocrine tumours (NET) are heterogenous group of tumours commonly arising from Gastro-pancreatic (GI) and pulmonary origins. Combination of bowel resection, disease related diarrhoea and somatostatin analogue therapy (SSA) can contribute to vitamin B12 deficiency (B12D). International guidelines do not suggest routine screening. Total serum cobalamin (B12) level can be falsely normal in patients with B12D. Cells take up B12 in the form of Holotranscobalamin (...

ea0086p367 | Thyroid | SFEBES2022

L-T3 Prescribing & Deprescribing - Single Centre Experience

Day Katie , Swe Myint Khin , Neupane Sankalpa , Swords Frankie , Ahluwalia Rupa

Introduction: 90-95% of patients with primary hypothyroidism respond well to levothyroxine (L-T4) therapy. A minority remain symptomatic despite optimised L-T4 therapy. There is limited evidence supporting the role of liothyronine (L-T3) in this subgroup of patients. By looking at 3- and 6-month trials, we aim to review our practice of L-T4/l-T3 therapy.Method: We reviewed medical and pharmacy records of all patients receiving L-T4/l-T3 therapy from Janu...

ea0062p26 | Poster Presentations | EU2019

A rare case of dual cerebral venous sinus thrombosis secondary to Thyroid storm

Khine Win , MacFarlane James , Lee Martin , Rice Katy , Swe Myint Khin

Background: Evidence suggested a hypercoagulable state in the context of hyperthyroidism. We presented a case of cerebral venous thrombosis (CVT), a rare but potentially fatal complication of the already high mortality thyroid storm.Case History: A 16year old boy with AspergerÂ’s syndrome was admitted with one-month history of non-specific illness and weight loss followed by 2 weeks of progressive frontal headaches and vomiting, weakness in left arm ...

ea0094p10 | Adrenal and Cardiovascular | SFEBES2023

Iatrogenic Cushing’s syndrome and Avascular necrosis of femoral heads following a drug to drug interaction of antiretrovirals and fluticasone inhaler

Bawden David , Jackson Portia , Pintilie Hannah , Swe Myint Khin , Ahmed Khaled

Background: Fluticasone is an inhaled steroid commonly used for asthma with low systemic bioavailability (~9%). We present a case of significant Iatrogenic CushingÂ’s syndrome when fluticasone was used simultaneously with antiretroviral therapy.Case: 27-year-old man was diagnosed with HIV in 2021. His antiretroviral therapy was simplified to GENVOYA (elvitegravir/cobicistat/tenofovir/alafenamide/emtricitabine) at the...

ea0094p27 | Adrenal and Cardiovascular | SFEBES2023

Evaluation of the hounsfield unit approach for streamlining investigations for adrenal incidentalomas

Tam Trevor , Saada Louis , Joseph Neetha , Chipchase Allison , Swe Myint Khin , Ahluwalia Rupa

Background: Adrenal incidentalomas (AIs) detected on pre surgical scans often present a logistical challenge due to the pressing need for preoperative exclusion of a phaeochromocytoma. Our local guideline recommends endocrinology referral for all AIs for further investigations, including pre clinic 24-hr urine metadrenalines. This approach can be time-consuming, particularly for patients awaiting unrelated surgery.Methods:</stron...

ea0094p45 | Neuroendocrinology and Pituitary | SFEBES2023

Phaeochromocytoma/Paraganglioma – Call for Education and More Screening

Yung Zhuang Choo Alwyn , Ahluwalia Rupa , Joseph Neetha , Saada Janak , McArdle Nicholas , Chipchase Allison , Rochester Mark , Manson-Bahr David , Maxwell Melanie , Swe Myint Khin

Background: Phaeochromocytomas & paragangliomas (PPGL) are rare neuroendocrine tumours presenting with symptoms of sympathetic overactivity, hypertension, or as adrenal incidentalomas.Study and results: A 24-year retrospective review of a U.K. single-centre PPGL service (2009 -2023) identified 61 cases (53 phaeochromocytomas/8 paragangliomas). Among these, 35 (57%) were females. Mean age of diagnosis was 56.35&pm;16....