Searchable abstracts of presentations at key conferences in endocrinology

ea0019p254 | Pituitary | SFEBES2009

Acromegaly: an audit of treatment outcomes

Gorick S , Powell K , Swords FM , Temple RC

Introduction: Guidelines suggest definition for cure in acromegaly is to achieve a nadir growth hormone (GH) <2 mU/l during a growth hormone suppression test and a normal IGF-1 level (Gustina 2000). Following an earlier retrospective audit (Brown et al. 2002), showing limited achieved cure success, we re-audited our patients.Methods: All patients with acromegaly were invited to undergo growth hormone suppression test and IGF-1measurement over ...

ea0015p221 | Pituitary | SFEBES2008

Gamma knife radiosurgery: a safe and effective treatment for acromegaly

Swords FM , Monson JP , Besser GM , Chew SL , Drake WM , Grossman AB , Plowman PN

We report the use of Gamma knife radiosurgery (GK) to 15 somatotroph adenomas. Eight patients had refractory acromegaly despite maximal conventional treatments: all had undergone conventional radiotherapy (CRT), mean interval between CRT and GK 15.6 years. Six had undergone surgery, two on more than one occasion. Five were receiving somatostatin analog therapy, one was receiving dopamine agonist therapy, one was on pegvisomant alone. All had radiologically defined disease, wel...