Searchable abstracts of presentations at key conferences in endocrinology

ea0015s67 | Obtaining funding for young endocrinologists | SFEBES2008

Clinical research fellowships: an insider’s account

Swords Francesca

Consultants have all done research and got publications, and juniors always seem to be too busy to do either. However, without direct experience, you have little chance of understanding research papers, let alone generating your own, and somehow you have to fill in that gap on your CV. There comes a time then, at which a clinical research fellowship suddenly seems rather attractive.The benefits of a period in research are obvious. A fellowship allows you...

ea0038p112 | Clinical practice/governance and case reports | SFEBES2015

Carbarmazepine and Cushing’s: a cautionary tale of assay interference mimicking disease

Tisdale Mie Mie , Swords Francesca

We present two cases, with apparently confirmed Cushing’s. Detailed clinical evaluation did not support the diagnosis, and carbamezepine interference was finally confirmed in both patients.Case 1: A 44-year-old man presented to a nephrologist with malignant hypertension. Routine investigation for secondary causes revealed hyperreninaemia with marked disparity of kidney size suggestive of renal infarction. 24 h urinary free cortisols (UFCs) were also...

ea0062p51 | Poster Presentations | EU2019

Steroid cell ovarian tumour presenting with severe hyperandrogenism

Rehman Shoib Ur , Brennan Sinead , Swords Francesca

A 69-year-old woman was referred with a 2 year history of frontal balding, deepening voice and weight loss. Past medical history included primary hypothyroidism, osteoarthritis, varicose veins and menopause at age of 50 years. Current medications included levothyroxine. She was otherwise very well and enjoyed heightened physical endurance – regularly cycling >60 miles with a group of male friends. On examination she was virilised with male pattern alopecia, marked fac...

ea0038p448 | Thyroid | SFEBES2015

Management of amiodarone induced thyrotoxicosis within the United Kingdom: is it time for a consensus guideline? A single centre retrospective review

Tisdale Mie Mie , Swords Francesca , Ahluwalia Rupa

Introduction: Amiodarone induced thyrotoxicosis (AIT) remains a diagnostic and therapeutic challenge. Broadly, AIT is classified as type 1 (underlying latent thyroid disorder) or type 2 (destructive thyroiditis). Despite being an on-going clinical conundrum, there is no U.K. wide guidance on management of AIT. We report a retrospective review of recent cases treated within our department as AIT.Methods: Data was collected for all patients referred to our...

ea0034p76 | Clinical practice/governance and case reports | SFEBES2014

Recovery of adrenal function in confirmed Addison's disease

Baxter Mark , Gorick Sondra , Swords Francesca

Background: Addison’s disease is characterised by immune mediated destruction of the adrenal glands. This process is widely deemed to be irreversible. We present a case of confirmed Addison’s disease where adrenal function appears to have spontaneously recovered.Case report: A 37-year-old presented in 1997 with classical Addison’s disease: pigmentation, dizziness, weight loss, and nausea. There was no relevant family history. Random cortis...

ea0034p168 | Neoplasia, cancer and late effects | SFEBES2014

A challenging case of hypokalaemic Cushing's crisis

Dunne Mary , Solomon Andrew , Swords Francesca

Background: Cushing’s syndrome derived from paraneoplastic ectopic ACTH production can present in dramatic fashion. We describe such a case that presented with severe hypokalaemia, involving significant diagnostic and management challenges.The case: A 66-year-old female was referred acutely to hospital by her GP after feeling weak and lethargic. She had profound hypokalaemia of 1.5 mmol/l (3.5–5.3) with normal renal function and had been normok...

ea0025p209 | Nursing practise | SFEBES2011

Audit of low dose dexamethasone suppression test to exclude androgen secreting tumours in hyperandrogenic women

Powell Katherine , Temple Rosemary , Swords Francesca

The low dose dexamethasone suppression test (LDDT) is used routinely to exclude Cushings. This test can also be used to exclude androgen secreting tumours in females with elevated testosterone levels through normalisation of, or >40% suppression of serum levels.We have audited the use of the LDDT to assess its value in investigating women with raised androgens, to ascertain whether it reduced the need for other investigations and to identify any prob...

ea0021p53 | Clinical practice/governance and case reports | SFEBES2009

An unusual presentation of polyendocrinopathy

Venu Maya , Marath Haris , Swords Francesca

A 52-year-old gentleman was referred for the evaluation of hypercalcaemia. He gave a four week history of feeling generally unwell with dizziness, abdominal discomfort, weight loss, nausea and vomiting. He was an ex-heavy smoker and was on Lithium for about 20 years for bipolar disorder. He had had a recent admission to hospital with sepsis, secondary to chest infection, with a brief ITU stay and was discharged only 3 weeks prior to the onset of current illness.<p class="a...

ea0019p239 | Pituitary | SFEBES2009

Familial prolactinoma occuring in association with SDHB mutation positive paraganglioma

Brahma Anupam , Heyburn Philip , Swords Francesca

A 33-year-old male presented with headache and visual loss in May 2003. MRI pituitary showed a large tumor arising from pituitary fossa extending to suprasellar cistern compressing the optic chiasm with features recent infarction. He subsequently underwent urgent trans-sphenoidal decompression and a necrotic prolactinoma was excised with full recovery of his vision. His prolactin level remained elevated and so he was treated with cabergoline. Further questioning revealed that ...

ea0018p13 | (1) | MES2008

Unusual hypoglycaemia: real or factitious?

Sharma Sanjeev , Swords Francesca , Dozio Nicoletta

Factitious hypoglycaemia is characterised by high insulin levels but accompanied with low Proinsulin and C-peptide levels and a negative sulfonylurea screenWe present a 54-year-old woman who was initially diagnosed with type 2 diabetes in 2002 and by 2004, she was converted to insulin treatment due to poor tolerance to Metformin. She also had a previous history of Manic depressive psychosis and treated with lithium.In the months pr...