ea0086p208 | Metabolism, Obesity and Diabetes | SFEBES2022
Schoonejans Josca
, Man Fan Hei
, Mitchell Alice
, Lovgren-Sandblom Anita
, Syngelaki Argyro
, Sukumar Nithya
, Periyathambi Nishanti
, Nicolaides Kypros
, Seed Paul
, Molinaro Antonio
, Marschall Hanns-Ulrich
, Saravanan Ponnusamy
, Williamson Catherine
Introduction: Bile acid (BA)-feeding and genetic manipulation of BA receptors affect glucose tolerance in rodent pregnancy. In non-pregnant individuals, serum BA profiles depend on BMI and ethnicity. The interaction between serum BAs, ethnicity, and BMI in gestational diabetes mellitus (GDM) remains poorly understood.Methods: Fasted serum samples were collected between 23-31 weeksÂ’ gestation. Experimental groups: lean or obese women of European (EU)...