Searchable abstracts of presentations at key conferences in endocrinology

ea0014p171 | (1) | ECE2007

Muscle mitochondrial function is impaired in patients with prior acromegaly

Szendrödi Julia , Zwettler Elisabeth , Schmid Albrecht Ingo , Chmelik Marek , Pacini Giovanni , Kacerovsky Gertrud , Schnack Christoph , Schernthaner Guntram , Wagner Oswald , Klaushofer Klaus , Roden Michael

Acromegaly is amongst other symptoms associated with myopathy, alterations of energy expenditure and insulin action which are mediated by growth hormone (GH) and insulin-like growth factors (IGFs). It is unclear to which extent these abnormalities remain after treatment. Thus, we examined glucose metabolism, intracellular fat deposition and mitochondrial function in patients with prior acromegaly (AM).Six AM (4f/2 m, age: 49±10 years, body mass inde...