Searchable abstracts of presentations at key conferences in endocrinology

ea0095p25 | Diabetes 1 | BSPED2023

Evaluating the impact of planned ward admissions in High HbA1c patients

Radhakrishnan Sijith , Makaya Taffy

Introduction: NICE guidelines recommend additional support is provided to CYP with a high HbA1c. Elective hospital admissions are one option for improving glycaemic control.Aims/objectives: To evaluate the implementation of, and impact on HbA1c of, planned admissions in CYP in our service.Methods: All planned admissions for management of sustained high HbA1c in patients with known ...

ea0095p146 | Pituitary and Growth 2 | BSPED2023

Predictive value of a basal LH instead of an LHRH test in assessing pubertal suppression in children on GnRH agonist therapy

Easa Habab , Makaya Taffy

Background: Historically, a second LHRH stimulation test has been the gold standard test for the evaluation of biochemical evidence of pubertal suppression in patients with central precocious puberty (CPP) following commencement of GnRH analogue therapy. However, this test is time-consuming, costly, and uncomfortable for patients.Aims/objective: To analyse the validity of the basal LH level as a predictor to the peak LH ...

ea0095oc6.4 | Oral Communications 6 | BSPED2023

Screening for coeliac disease in paediatric patients diagnosed with Graves’ Disease

Bendor-Samuel Owen , Makaya Taffy

Introduction: Our current local management guidelines for Graves’ Disease (GD) in children and young people (CYP) do not include routine screening for coeliac disease (CD). However, ad hoc testing of patients in this cohort pointed to a high incidence of positive tissue transglutaminase (TTG) results.Aims/Objectives: 1. To determine the incidence of CD in patients in our service diagnosed with GD. 2. To establish if...

ea0039ep12 | Adrenal | BSPED2015

A case of a rare adrenocortical tumour mimicking neuroblastoma

Rozario Kavitha , Ryan Fiona , Makaya Taffy

Presentation and investigation: A 10-month-old girl presented with a bluish lump on the left side of her abdomen which was increasing in size. An abdominal mass was palpable on examination. An ultrasound showed a large, partly calcified mass measuring 9×6×9 cm arising from the left adrenal gland. There were also calcified lesions in her liver and lungs suggesting metastsis. MRI confirmed the ultrasound finding plus detected an intraspinal deposit with some cord compr...

ea0039ep99 | Other | BSPED2015

Positive thyroid peroxidase antibodies at diagnosis of type 1 diabetes mellitus is associated with earlier onset of thyroid disorders

Rozario Kavitha , Hlaing Su Su , Makaya Taffy

Aims: To assess the relationship between thyroid peroxidase (TPO) antibodies and the development of thyroid disorders in children with type 1 diabetes mellitus (T1DM).Method: TPO antibody status and duration of diabetes at diagnosis of thyroid disorder were cross-sectionally examined in all children attending the Oxford T1DM service (n=342, male:female ratio 1:0.8).Results: Twenty patients were identified with thyroid como...

ea0058p045 | Diabetes | BSPED2018

A rare and unexpected cause of diabetes in a teenager

Makaya Taffy , Ali Aishatu , Basu Supriyo

Introduction: Pancreatogenic diabetes (Type 3c diabetes-T3cDM) is rare in children, and frequently underdiagnosed. The prevalence is 5–10% of all adult diabetes cases in the developed world. Over 78% of people with T3cDM have chronic pancreatitis.Case: A 15-year old presented with polyuria, polydipsia, abdominal pain, weight loss (WL) and a three-generational family history of type-1 (T1DM) and type-2 diabetes mellitus (T2DM). Examination revealed m...

ea0045oc7.5 | Oral Communications 7- Diabetes | BSPED2016

Establishing a paediatric diabetes sports service

Makaya Taffy , Frohock Anne Marie , Lumb Alistair

Background: There is growing recognition of the importance of sports/exercise in children and young people (CYP) with type 1 diabetes (T1DM) [NICE guidance 1.2.47–1.2.53]. In 2014 our Paediatric Diabetes service set up a Diabetes Sports clinic run by a paediatric diabetologist and dietician and an adult diabetologist. Appointments were offered to families of CYP with T1DM who are ‘elite sportspersons’–performing at competitive levels, or regional/national l...

ea0045oc8.1 | Oral Communications 8- Diabetes | BSPED2016

Coeliac disease screening in children with type 1 diabetes mellitus: Is it time for a new approach?

Makaya Taffy , Patel Sejal , Duckworth Eleanor

Objectives: Recently updated NICE guidelines (2015) on coeliac screening for children with Type 1 diabetes mellitus (T1DM) recommend just one initial screen for coeliac disease (CD) at the time of T1DM diagnosis and thereafter only if symptomatic. This is in contrast to the recommendation for on-going annual screening for autoimmune thyroid disease (ATD). Our unit has historically performed annual screening for both ATD and CD. Our study aimed to establish whe...

ea0058p038 | Thyroid | BSPED2018

Long-term outcomes of thyroid function in babies with Down syndrome and congenital or early hypothyroidism

Bendor-Samuel Owen , Basu Supriyo , Robertson Clare , Makaya Taffy

Introduction: Children with Down syndrome (trisomy-21/T21) are at risk of developing congenital and early (diagnosed ≤1 year) hypothyroidism. Our current monitoring follows the Down Syndrome Medical Interest Group (DSMIG) guidance: performing thyroid function tests (TFT) at birth and 12 months.Aims/objectives: 1) Determine the incidence of congenital/early hypothyroidism in babies with T21 and determine long-term thyroid function outcomes (by age 4...

ea0033p49 | (1) | BSPED2013

Precious puberty in an infant is not normal

Lamabadusuriya Harshan , Wolfenden Helen , Makaya Taffy , Wheeler Kate , Ryan Fiona

Background: A 5-month-old girl presented with a history of acute abdominal distension over several weeks. Three weeks previously she had developed pubic hair, and some early breast development. The GP had reassured parents on two occasions that this was normal. On examination she had Tanner breast stage 3 bilaterally, pubic hair stage 3, mild cliteromegaly, and gross abdominal distension.Investigations: An ultrasound scan revealed a massively enlarged ri...