Endocrine Abstracts

Introduction: The commonest complications post trans-sphenoidal surgery is diabetes insipidus and the development of anterior pituitary hormone deficiencies. Other complications include meningitis, CSF leak, visual deterioration, haemorrhages and transient hyponatremia. We present a case of pituitary abscess 6 months post pituitary surgery who presented with viral meningitis and panhypopituitarism.Case report: A 55-year-old lady presented with a 3 weeks ...

Introduction: The incidence of agranulocytosis with thionamide therapy is uncommon, ranging between 0.2 and 0.5 percent. Most reports document agranulocytosis after short duration of high dose Carbimazole in older patients. We report a 32-year-old lady with Graves’ disease who developed neutropaenic sepsis secondary to Carbimazole therapy on 5 mg daily and on treatment for the last 13 months.Case report: Our patient was diagnosed with Graves’s ...

Introduction: We report a patient with hypercalcaemia secondary to parathyroid hormone related peptide (PTHrp) from metastatic oesophageal cancer and co-existing primary hyperparathyroidism.Case report: A 52-year-old lady was admitted to the hospital with a 2-week history of right scapula pain, reduced appetite and weight loss.Blood test revealed an adjusted calcium of 3.99 nmol/l (NR 2.1–2.55 nmol/l), PTH of 147 ng/l (NR 15&#...

Introduction: Obstructive sleep apnoea (OSA) is common and frequently found in patients with obesity and type 2 diabetes mellitus. This case report shows the infrequently documented link between OSA and type 1 diabetes and highlights the need to confirm the type of diabetes especially in complex and atypical cases.Case report: A 44-year-old gentleman, with a BMI of 34, was diagnosed with type 2 diabetes and was treated with metformin and given lifestyle ...

Introduction: The short synacthen test (SST) is commonly used to assess the hypothalamic pituitary adrenal (HPA) axis in clinical practice. We evaluated the underlying clinical conditions pre-empting the request for a SST in a general medical ward and the adequacy of clinical follow up of patients with suboptimal responses to the test.Methods: All patients with suboptimal SST results (30 min cortisol level 450–540 nmol/l) performed in the Acute Asse...