Searchable abstracts of presentations at key conferences in endocrinology

ea0032p415 | Diabetes | ECE2013

Association between type 1 diabetes and oral health status

Poplawska-Kita Anna , Siewko Katarzyna , Szpak Piotr , Krol Beata , Telejko Beata , Mysliwiec Janusz , Stokowska Wanda , Gorska Maria , Szelachowska Malgorzata

Aims: We assessed periodontal status in patients with type 1 diabetes and healthy individuals in relation to their glycemic control, smoking, and inflammatory biomarkers.Methods: Periodontal status was examined in 107 patients with type 1 diabetes and 40 controls, using oral hygiene index (OHI), community periodontal index (CPI) and teeth number. CPI values of 0–2 and 3–4 were classified as non-periodontitis and periodontitis respectively. Bloo...

ea0020p121 | Thyroid | ECE2009

The incidence of thyroid cancer in the North-Eastern Region of Poland: a twelve year follow-up

Zonenberg Anna , Telejko Beata , Nikolajuk Agnieszka , Siewko Katarzyna , Zimnoch Lech , Dadan Jacek , Kinalska Ida , Gorska Maria

Before the introduction of mandatory salt iodination in 1997 the North-Eastern Region of Poland was known to be a moderate iodine deficiency area. It was also exposed to ionizing radiation after the Chernobyl accident in 1986. The aim of the present study was to evaluate the descriptive epidemiological features of incident thyroid cancers diagnosed among the residents of this area between 1996 and 2007. The Regional Cancer Surveillance Program was used to collect data on 834 n...

ea0014p73 | (1) | ECE2007

Circulating pro- and anti-inflammatory cytokines in women with gestational diabetes

Kuzmicki Mariusz , Telejko Beata , Zonenberg Anna , Szamatowicz Jacek , Kretowski Adam , Nikolajuk Agnieszka , Gorska Maria

Gestational diabetes mellitus (GDM) identifies a population of women at high risk of subsequent type 2 diabetes mellitus, representing an early stage in the natural history of the disease. Systemic inflammation is associated with the development of type 2 diabetes but the data concerning pro- and anti-inflammatory cytokines in patients with GDM are limited. The aim of our study was to investigate serum concentrations of interleukin-8 (IL-8), IL-18 and IL-10 in pregnant women w...

ea0041ep463 | Diabetes (to include epidemiology, pathophysiology) | ECE2016

Interleukin-6, interleukin-15 concentrations and insulin resistance in autoimmune diabetes

Siewko Katarzyna , Zielinska Anna , Maciulewski Rafal , Poplawska-Kita Anna , Telejko Beata , Lipinska Danuta , Gorska Maria , Szelachowska Malgorzata

Background: Interleukin-15 and -6 play a role in an inflammation, autoimmune, infectious and cancerous processes. Their increased concentrations were observed in psoriasis, asthma, multiple sclerosis and type 2 diabetes. However, the role of IL-15 and IL-6 in autoimmune diabetes (AD) pathogenesis is still unknown.Aim: The aim of our study was to assay circulating IL-15 and IL-6 levels in newly diagnosed AD patients, their I° relatives and healthy co...

ea0037gp.26.02 | Thyroid – hypothyroidism | ECE2015

High serum IgG4 concentrations in patients with Hashimoto's thyroiditis

Poplawska-Kita Anna , Kosciuszko-Zdrodowska Maria , Siewko Katarzyna , Telejko Beata , Hryniewicka Justyna , Milewski Robert , Szelachowska Malgorzata , Gorska Maria

Purpose: Recent reports strongly suggest that at least some cases of Hashimoto’s thyroiditis (HT) may be closely associated with IgG4-related disease. In the present study we aimed to find out, whether the measurement of serum IgG4 allows for an identification of distinct types of HT, with different clinical, sonographic and serologic characteristics.Methods: The group studied consisted of 53 patients with HT and 28 healthy individuals. All the part...

ea0035p367 | Diabetes (epidemiology, pathophysiology) | ECE2014

Serum cytokines and proinflammatory markers in first degree relatives of patients with type 1 diabetes

Szelachowska Malgorzata , Siewko Katarzyna , Poplawska-Kita Anna , Telejko Beata , Zielinska Anna , Maciulewski Rafal , Lipinska Danuta , Gorska Maria

Background and aims: In patients with type 2 diabetes, elevated tumor necrosis factor α (TNFα), C-reactive protein (CRP), chemerin, fetuin-A, have been reported. However, it is not entirely clear whether these alterations in adipokine serum concentrations are already present in prediabetic states and in type 1 diabetes. The aim of the study was to investigate whether adipokine profiles (chemerin, fetuin-A, TNFα) and inflammatory markers (CRP) are associated with...

ea0035p368 | Diabetes (epidemiology, pathophysiology) | ECE2014

Increased prevalence of anti-thyroid and anti-gastric parietal cell antibodies in first degree relatives of patients with type 1 diabetes

Siewko Katarzyna , Poplawska-Kita Anna , Telejko Beata , Maciulewski Rafal , Zielinska Anna , Lipinska Danuta , Gorska Maria , Szelachowska Malgorzata

Aim: It is well known that T1D is associated with other autoimmune diseases. The aim of this study was to compare the prevalence of various auto-antibodies in first-degree relatives of patients with T1D and healthy individuals with negative family history of diabetes.Material and methods: The group studied consisted of 90 relatives and 60 healthy individuals. Serum concentrations of antibodies to anti-21-hydroxylase (21-OH-Abs), anti-gastric parietal cel...

ea0035p978 | Thyroid (non-cancer) | ECE2014

Body mass analysis in patients with Hashimoto thyroiditis

Poplawska-Kita Anna , Siewko Katarzyna , Telejko Beata , Kosciuszko-Zdrodowska Maria , Hryniewicka Justyna , Szelachowska Malgorzata , Milewski Robert , Gorska Maria

Introduction: Thyroid hormones deficiency in the course of subclinical and overt hypothyroidism is frequently related to the increased body mass, reduced thermogenesis and metabolic rate however the pathogenesis of improper body mass in Hashimoto thyroiditis (HT) patients is still an open question. Therefore, in the present study we compared body mass and body composition between the patients with Hashimoto thyroiditis who were in clinical and hormonal euthyreosis and healthy ...

ea0014p328 | (1) | ECE2007

The changes in the incidence of nodular goitre, thyroid cancer and urine excretion of iodine in the inhabitants of north eastern Poland in 1997 and 2005

Zonenberg Anna , Zarzycki Wieslaw , Telejko Beata , Modzelewska Anna , Nikolajuk Agnieszka , Rybaczuk Mikolaj , Dzieciol Janusz , Siewko Katarzyna , Kinalska Ida , Gorska Maria

A higher incidence of nodular goitre and less differentiated types of thyroid carcinoma have been observed in iodine deficient regions. North-Eastern Poland was an area with a moderate deficiency of iodine until the introduction of the mandatory salt iodination in 1997 (30±10 mg KJ/kg NaCl). The aim of our study was to compare the incidence of goitre, thyroid carcinoma and urine excretion of iodine in the inhabitants of the North-Eastern Region of Poland in 1997 and 2005....

ea0035p392 | Diabetes (epidemiology, pathophysiology) | ECE2014

Resistin mRNA expression in fat and placental tissue of patients with gestational diabetes

Szamatowicz Michal , Wawrusiewicz-Kurylonek Natalia , Kuzmicki Mariusz , Telejko Beata , Wilk Juliusz , Pliszka Justyna , Lipinska Danuta , Szamatowicz Jacek , Kretowski Adam , Gorska Maria

Introduction: Resistin is a cysteine–rich adipokine that was originally described as a molecular link between obesity and insulin resistance. Our previous study showed higher serum resistin levels in patients with gestational diabetes mellitus (GDM) in comparison with healthy pregnant women however conflicting results have been reported by other authors. Therefore in the present study we investigated whether there were significant differences in resistin mRNA expression i...