Searchable abstracts of presentations at key conferences in endocrinology

ea0081p442 | Reproductive and Developmental Endocrinology | ECE2022

Energy deficit as a cause of transient male hypogonadotropic hypogonadism: a successful resolution of a primary infertility

Benido Silva Vania , Teresa Pereira Maria , Rossano Louro Nuno , Barreiro Marcia

Introduction: Caloric restriction combined with overtraining can result in a total body energy deficit, which in turn is associated with multiple deleterious endocrine consequences, including hypogonadotropic hypogonadism. This can be a reversible cause of primary infertility, but its occurrence in men is still poorly recognized.Case Report: We report a case of a 39-year-old male evaluated in an urology appointment for primary infertility. He had a histo...

ea0056p1112 | Thyroid (non-cancer) | ECE2018

Levothyroxine absorption test: a safe help for difficult cases

Lopes Ana , Teresa Pereira Maria , Lito Pedro , Freitas Claudia , Teixeira Sofia , Cardoso Helena

Levothyroxine (L-T4) is the mainstay of treatment of hypothyroidism. Marked elevation of thyrotropin (TSH) in patients on high replacement doses is rare and can result from malabsorption, drug interaction or poor compliance. The levothyroxine absorption test is required to distinguish these causes and has proved to be safe. This test measures the serum free thyroxine (FT4) response to 1 mg of oral L-T4 over 4–24 h.Clinical cases: Case no 1: A 28-yea...

ea0073aep629 | Thyroid | ECE2021

Long-term outcomes of radioiodine therapy in toxic solitary thyroid nodules

Puga Francisca , Teresa Pereira Maria , Cláudia Freitas , Helena Cardoso Maria

IntroductionThe toxic solitary thyroid nodule is a major cause of hyperthyroidism, especially in iodine-deprived regions. The most widely used therapy is iodine-131, which is effective in achieving normal thyroid function and reducing nodule dimensions, however, it may induce hypothyroidism. The aim of this study was to evaluate the outcomes of radioiodine therapy in patients with toxic solitary nodules and to determine predictive factors for the develop...

ea0099ep889 | Pituitary and Neuroendocrinology | ECE2024

Cyclic cushing’s syndrome: understanding the patterns of a complex endocrine disorder

Tavares da Silva Beatriz , Martins Fernandes Andreia , Almeida Raquel , Teresa Pereira Maria , Amaral Claudia

Introduction: Cyclic Cushing’s Syndrome is an uncommon disorder characterized by recurrent episodes of elevated cortisol levels, alternating with periods of normal cortisol secretion. These cycles of hypercortisolism can occur at regular or irregular intervals, ranging from days to years between episodes.Case presentation: A 57-year-old woman evaluated at the Endocrinology Outpatient Clinic because of symptoms of hypercortisolism with 18 months of e...

ea0070aep1101 | Hot topics (including COVID-19) | ECE2020

Measurement of calcitonin in nodular thyroid disease approach: The experience of a tertiary centre

Benido Silva Vânia , Teresa Pereira Maria , Carlos Oliveira José , Freitas Cláudia , Helena Cardoso Maria

Introduction: It is universally accepted that calcitonin (CT), a hormone secreted by the parafollicular cells of the thyroid, is a specific, sensitive and early marker of Medullary Thyroid Carcinoma (CMT), with higher diagnostic accuracy than fine needle aspiration biopsy(FNAB). However, the routine measurement of serum CT during assessment of nodular thyroid disease (NTD) remains controversial due to rarity of this cancer and possible false positive results.<p class="abst...

ea0073ep111 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

’Not everything is as it seems’ – a case report of Ketosis-Prone diabetes

Guilherme V. de Assunção , Fonseca Liliana , Benido Silva Vania , Teresa Pereira Maria , Vilaverde Joana , Dores Jorge , Helena Cardoso Maria

IntroductionKetosis-Prone Diabetes (KPD) is a heterogeneous condition that shares clinical characteristics of type 1 and type 2 diabetes. It is usually a challenging diagnosis because patients are prone to develop diabetic ketoacidosis (DKA) without having the classic clinical phenotype of autoimmune type 1 diabetes.Case reportA Caucasian 26-years-old female with known history of renal transplant, morbid obes...

ea0070aep29 | Adrenal and Cardiovascular Endocrinology | ECE2020

Treatment outcomes in 198 patients of the portuguese adrenocortical carcinoma register

Nunes da Silva Tiago , Catarino Diana , Paiva Isabel , Chaves Carolina , Costa Claudia , Castro Raquel , Paula Marques Ana , Souteiro Pedro , Pereira Maria , Machado Catarina , Belo Carlos , Simões Helder , Cortes Luisa , Pereira Bernardo , Anselmo João , Sapinho Inês , Gonçalves Ferreira Ana , Teresa Pereira Maria , Fonseca Liliana , Fernandes Isabel , Rita Elvas Ana , Donato Sara , Martins Anabela , Fajar Laura , Martinho Mariana , Garrido Susana , Ferreira Marta

Introduction: Adrenocortical carcinoma (ACC) is a rare entity, usually associated with a poor prognosis. There are still many areas of uncertainty regarding its approach.Methods: A Portuguese ACC register was established in 2020, including information from 24 endocrine centres. Kaplan-Meier was used to calculate overall survival and recurrence; log- rank test to assess survival and progression free survival (PFS) differences between groups; cox-regressio...