Searchable abstracts of presentations at key conferences in endocrinology

ea0009p206 | Clinical | BES2005

Thionamide resistant thyrotoxicosis - three illustrative cases

Lee S , Kapoor D , Thomas W , Jones T

Antithyroid drug (ATD) resistant thyrotoxicosis raises difficult management issues. We describe three recent cases of apparent refractory thyrotoxicosis.Case 1: A 31 year old woman presented in July 2003 with thyrotoxicosis. Despite treatment with carbimazole (CBZ) 20 milligrams tds, serum free thyroxine (FT4) concentrations remained around 60 picomoles per litre (11-20). In October, CBZ dose was increased to 40 milligrams bd and dexamethasone 2 milligra...

ea0005p15 | Clinical Case Reports | BES2003

Rapid enlargement of thyroid neck swelling in two patients with thyroid dysfunction

Campbell H , Kapoor D , Thomas W , Jones T

We report two ladies who presented with thyroid dysfunction associated with neck swelling. In both cases within ten days of consultation they developed rapid enlargement of their mass associated with marked swelling of an arm.Case 1. A 63 year old lady developed sudden onset of a thyroid swelling associated with a new diagnosis of primary hypothyroidism . She had lost weight and felt tired. On examination she had a moderately enlarged woody goitre, there was no associated ...

ea0034p166 | Growth and development | SFEBES2014

Differential effects of grazing and meal feeding on skeletal growth and femoral strength in male rats

Tilston Thomas W , Hopkins Anna L , Brown Richard C , Arms-Williams Bradley , Evans Sam L , Wells Timothy

The pattern of food consumption has a profound influence on metabolic hormone secretion, but until recently only crude manipulations of feeding events have been possible in rodents. Using a CLAMS-based system to overcome this problem, we have investigated the effect of 3 weeks of grazing (consumption of 1/24th of the total daily food intake of ad libitum-fed controls every 30 min during the dark phase (18.00–06.00 h)) and meal feeding (three 1-h periods of ad...

ea0081p175 | Pituitary and Neuroendocrinology | ECE2022

Low post-operative cortisol after TSS for pituitary surgery predicts short term but not long term remission

Karunakaran Vanitha , Okasha Mohamed , W Thomas Nick , Barazi Sinan , Maratos Eleni , C Whitelaw Benjamin , Gilbert Jackie , V Carroll Paul , Shapey Jonathan , J B Aylwin Simon

Background: It is generally accepted that a post-operative cortisol of <50 nmol/l is a good predictor of long-term remission following trans-sphenoidal surgery (TSS).Aim: We wished to determine the rate of late recurrence and need for consequent intervention in patients who had initial biochemical remission after TSS for pituitary dependent Cushing’s.Methods: We performed a retrospective analysis of our patients who underw...