Searchable abstracts of presentations at key conferences in endocrinology

ea0016s26.2 | New therapeutic options in diabetes | ECE2008

Plasticity of human pancreatic beta cells

Otonkoski Timo

Understanding how beta-cells maintain themselves in the adult pancreas is important for the development of strategies aimed at ameliorating or ideally curing different forms of diabetes. There has been much debate over whether beta-cell proliferation, as a means of self-renewal, predominates compared to the existence and differentiation of a pancreatic stem cell or progenitor cell population. Based on studies in the mouse, both principles can be demonstrated, although in norma...