Searchable abstracts of presentations at key conferences in endocrinology

ea0022p782 | Thyroid | ECE2010

Mild hypothyroidism in young patients with congenital heart defects: association with 22q11.2 microdeletion

Elena Passeri , Marcello Frigerio , Tiziana De Filippis , Rea Valaperta , Elena Costa , Laura Fugazzola , Patrizia Porazzi , Davide Calebiro , Carmelo Arcidiacono , Mario Carminati , Bruno Ambrosi , Luca Persani , Sabrina Corbetta

Congenital hypothyroidism (CH) is frequently associated with congenital heart defects (CHD). Thyroid defects may have a higher prevalence in children with CHD as embryonic thyroid gland share nuclear transcription factors with heart and great vessels during organogenesis. We investigated thyroid function in 325 children (165 M/160 F, aged 0.2–15.4 years), affected by CHD. Patients with Down syndrome, recent administration of iodinated contrast agents, low T3 sy...