Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep55 | Adrenal cortex | ECE2015

Rare case of ectopic ACTH secreting tumour causing cyclical Cushing's syndrome

Acharya Jayashekara , Akavarapu Sriranganath , Abbara Ali , Parvathy Valsalakumari , Todd J F

We are reporting a rare case of ectopic ACTH secreting tumour causing cyclical Cushing’s syndrome. A 63-year-old lady presented in March 2013 with tiredness and bilateral leg swelling and weakness associated with easy bruising. She was admitted to local hospital in April 2013 with worsening proximal myopathy and peripheral oedema. Her midnight cortisol was elevated at 1710 nmol/l. ACTH 610 mU/l, prolactin 476 mU/l, GH 0.21 IU/l, TSH 0.73 mU/l, free T4 of 11.0 p...

ea0018p9 | (1) | MES2008

Challenges in the management of Cushing's syndrome in the severely ill patient

Fountain A E C , McGowan B M C , Chaudhuri O , Saha S , Field B C T , Dhillo W , Todd J F , Goldstone A P , Martin N M , Meeran K , Tan T

We present a 57-year-old female with Cushing’s syndrome characterised by new type 2 diabetes, hypertension, weight gain, bruising, proximal myopathy and depression. She also had poorly-healing cellulitic ulcers on both legs. Investigations: hypokalaemia and ACTH-dependent Cushing’s syndrome. Low dose dexamethasone suppression test: T=0 ACTH 85 ng/l, cortisol 907 nmol/l, T=48 h cortisol 807. High dose dexamethasone suppression test failed to suppr...