Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep828 | Pituitary: clinical | ECE2015

A case of adrenal crisis secondary to ipilimumab-induced autoimmune hypophysitis

Todd Anna , Thiraviaraj Athinyaa

A 42-year-old man undergoing ipilimumab therapy for stage IV metastatic melanoma presented after his third dose with vomiting, abdominal pain, hypotension, and pyrexia. He was treated as a presumed line sepsis. Four days prior to admission, thyroid function test showed T4 of 7.9 pmol/l and TSH 0.02 mU/l and he was treated with levothyroxine. A pituitary profile was carried out on admission and the results were as follows, cortisol was 24 nmol/l, testosterone <0....

ea0104p205 | Thyroid | SFEIES24

Selenium prescribing for thyroid eye disease in NI – the exponential rise

Aamir Shahzad Muhammad , Nugent Ailish , Hunter Amy , Lewis Anthony , Loughrey Ben , Ahmed Doua , Casey Geraldine , McHenry Claire , Courtney Hamish , Wallace Helen , Wallace Ian , Lindsay John , Darrat Milad , Johnston Philip , Haq Rizwan , D'Arcy Robert , Kamalarajah Sri , Hunter Steven , White Steven , Graham Una , McNabb Bernadette , McElwaine Fred , McMullan Paul , Harper Roy , Elhassan Samah , Shakeel Majeed Muhammad , Mustafa Shaikh Ghulam , Neely Andrew , Todd Anna , Sandhu Farooq , Smyth Jayna , Bradley Una , McConnell Mae , Kennedy Adele , Hameed Ali , Hamill Connor , Rooney Des , McKeever Edward , McCracken Emma , Black Neil , Kelly Rhys , Cartmill Barry , Bonanos Efstathios , Gordon Aileen , Woodside Jayne , Mullan Karen

Selenium (Se) supplementation is recommended by the European Group (EUGOGO) for mildly active TED (200 mg/day for six-months) based on a seminal RCT which reported slowing of disease progression vs placebo. Treatment in Se deficient geographical areas may be particularly important. We recently reported Se deficiency in a cohort of 240 pregnant women in NI. The TEAMeD-NI group was set up in 2019 as part of the UK-wide quality improvement program to take a proactive approach to ...