Searchable abstracts of presentations at key conferences in endocrinology

ea0063p22 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

The frequency of confirmed primary hyperaldosteronism in patients with high aldosteron renin ratio

Ozdemir Didem , Topaloglu Oya , Aydogan Leyla , Ersoy Reyhan , Cakir Bekir

Introduction: The aldosterone-to-renin ratio (A/R) is the most frequently used screening test for primary hyperaldosteronism (PH) and a confirmation test is recommended when it is high. We aimed to determine the frequency of PH in patients with high A/R and investigated possible clinical features that might help to prevent unnecesary confirmation tests.Method: Patients who underwent saline infusion test because of high A/R (>3.8) were retrospectively...

ea0022p815 | Thyroid | ECE2010

Evaluation of theurapeutic modalities in Graves' hyperthyroidism

Yalcin Yavuz , Topaloglu Oya , Berker Dilek , Isik Serhat , Guler Serdar

Objective: Currently there are three well-established treatment options for hyperthyroid Graves’ disease (GD): antithyroid drug therapy with thionamides, radioactive iodine (RAI) treatment with (131)I, and surgery. The aim of this study was to investigate retrospectively theurapeutic options of the patients with GD treated at outpatient clinics of Endocrinology and Metabolism between January 2007 and December 2009.Methods: We evaluated 122 patients ...

ea0081oc14.5 | Oral Communications 14: Late Breaking | ECE2022

The effect of multiple passes to the same thyroid nodule in the fine needle aspiration biopsy session on obtaining adequate and/or the AUS/FLUS cytological result

Dellal Kahramanca Fatma Dilek , Cuhaci Seyrek Fatma Neslihan , Alkan Afra , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Aim: To determine whether multiple fine needle passes to the same thyroid nodule in the fine needle aspiration biopsy (FNA) session affect sufficient and/or atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) cytological result.Materials and Methods: Ultrasonography (US) and cyto-histopathology results of the nodules of patients who were diagnosed with thyroid nodules and underwent FNA between May-August 2021 wer...

ea0063p454 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Selective arterial calcium stimulation test in two cases with occult insulinoma

Ahmadova Konul , Tam Abbas Ali , Topaloglu Oya , Akkan Koray , Bostancı Birol , Ersoy Reyhan , Cakir Bekir

Introduction: 80–90% of insulinomas are smaller than 2 cm, equally located in the head, body and tail of pancreas. Computer tomography (CT) is 75%, magnetic resonance imaging (MRI) is 55–90%, endoscopic ultrasonography (EUS) is 85–95% and selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma which could not be located by conventional methods and evaluated with SAC...

ea0041ep76 | Adrenal cortex (to include Cushing's) | ECE2016

A rare case of ectopic ACTH syndrome originated from malignant renal paraganglioma

Tutal Esra , Yilmazer Demet , Demirci Taner , Cakal Erman , Cakir Evrim , Celep Bahadir , Topaloglu Oya , Delibasi Tuncay

Introduction: Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of non-pituitary ACTH-secreting tumor leads to the Cushing’s syndrome. Herein, we present a case with Cushing’s syndrome, which is diagnosed ACTH-secreting renal malignant paraganglioma.Case: A 40-year-old woman presented with a 5 month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation,...

ea0041ep295 | Clinical case reports - Pituitary/Adrenal | ECE2016

A patient with radiological dilemma: hemorrhagic pituitary adenoma or rathke’s cleft cyst?

Faki Sevgul , Topaloglu Oya , Bilginer Cuneyt , Cuhaci Neslihan , Ercan Karabekir , Ersoy Reyhan , Cakir Bekir

Introduction: Rathke’s cleft cyst is one of the pituitary non-adenomatous tumors that found in about 20% of pituitary glands at autopsy. Symptomatic Rathke’s cleft cysts are rarely, but these cysts can cause serious medical problems associated with compression of the pituitary gland, pituitary stalk, optic nerve or hypothalamus. Here, we report a rare case of 73 years old man with sudden onset headache due to Rathke’s cleft cyst present with symptoms and radiolo...

ea0041ep301 | Clinical case reports - Pituitary/Adrenal | ECE2016

Acromegaly in a male patient with Kleinfelter syndrome

Burcak Polat Sefika , Bestepe Nagihan , Topaloglu Oya , Bal Ercan , Ersoy Reyhan , Cakir Bekir

Introduction: Klinefelter syndrome is known as the set of symptoms that result from two or more X chromosomes in males. There is no known association of this syndrome with GH hypersecretion. The most remarkable symptom is gigantism and it can also be observed in androgen deficient states as such as the Klinefelter syndrome and some more genetic syndromes such as the Sotos syndrome, the Marfan syndrome, the homocystinuria, and the fragile X-syndrome. Herein we presente...

ea0041ep367 | Clinical case reports - Thyroid/Others | ECE2016

A case with atypical parathyroid lipoadenoma presented with severe hypercalcemia and skeletal deformities

Bilginer Cuneyt , Topaloglu Oya , Cuhaci Neslihan , Dumlu Gurkan , Yazgan Aylin Kilic , Ersoy Reyhan , Cakir Bekir

Introduction: Parathyroid lipoadenoma (PLA) is a rarely seen, benign variant of parathyroid adenoma (PA). However, PA usually consists of uniform, polygonal chief cells with a few nests of oxyphil cells, PLA consists of similar histologic features, but with an abundance of fat cells. Additionally, PLA may be functional with the secretion of parathyroid hormone (PTH) or non-functional. Here, we present a case of atypical PLA presented with severe hypercalcemia and skeletal defo...

ea0041ep938 | Pituitary - Clinical | ECE2016

Tolosa Hunt syndrome involving the pituitary: a case report

Polat Sefika Burcak , Topaloglu Oya , Bal Ercan , Ersoy Reyhan , Cakır Bekir

Introduction: Tolosa Hunt syndrome (THS) is described as unilateral orbital pain associated with paresis of one or more of the third, fourth and/or sixth cranial nerves caused by a granulomatous inflammation in the cavernous sinus, superior orbital fissure or orbit. Pituitary gland is rarely involved in this syndrome. Herein we represented a case with hypophysitis with Tolosa Hunt who was operated with the suspicion of pituitary adenoma.Case: A 63-year-o...

ea0041ep988 | Thyroid (non-cancer) | ECE2016

Malignancy is associated with microcalcification and AP/T ratio in ultrasonography, but not with Hashimoto’s thyroiditis in histopathology in patients with thyroid nodules evaluated as Bethesda Category III (AUS/FLUS) in cytology

Topaloglu Oya , Baser Husniye , Cuhaci Neslihan , Sungu Nuran , Yalcin Abdussamed , Ersoy Reyhan , Cakir Bekir

Introduction: The predictors of malignancy are important for decision of appropriate management in nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). Our aim was to determine the ultrasonographical, clinical and biochemical predictors of malignancy in these patients.Methods: A total of 427 patients with Bethesda Category III (AUS/FLUS) thyroid nodules were included in this retrospective study. We d...