ea0094op7.2 | RET and Endocrine Cancer | SFEBES2023
Frizelle Isolda
, Velusamy Anand
, McGowan Barbara
, Breen Louise
, Izatt Louise
, Touska Philip
, Christodoulou Dimitra
, Eftychiou Nicolas
, Hassan Fahim-ul
, Carroll Paul
Introduction: Pheochromocytoma and Paraganglioma (PPGL) are neuroendocrine tumours arising from chromaffin cells in the adrenal medulla or ganglia in the autonomic nervous system. ~40% of PPGL arise due to germline mutation (commonly SDHx) and sporadic tumours frequently have causative somatic mutations. 15-20% of PPGL behave in a malignant manner. ~95% PPGL express somastostatin receptors and are GaDOTATATE avid. Lutathera® is a commercially available PR...