Searchable abstracts of presentations at key conferences in endocrinology

ea0022p48 | Adrenal | ECE2010

Combined primary aldosteronism and preclinical Cushing's syndrome due to a large adrenocortical adenoma

Ciric Jasmina , Beleslin Biljana , Stojkovic Mirjana , Trbojevic Bozo , Zarkovic Milos

The rarest causes of primary aldosteronism are aldosterone producing carcinoma, ectopic aldosterone secretion and familial aldosteronism. There are also few cases reported of aldosterone and cortisol tumor cosecretion. We present a 38-year-old woman admitted to our hospital because of resistant hypertension, large adrenal tumor and hypokalemia. At age 32 hypertension was diagnosed, but routine laboratory and abdominal ultrasound examination were normal. Few months before admis...

ea0032p290 | Clinical case reports - Thyroid / Others | ECE2013

Neurogenic hypertension as a case report

Nisic Tanja , Stojkovic Mira , Stojanovic Milos , Ciric Jasmina , Beleslin Biljana , Lalic Tiana , Zarkovic Milos , Trbojevic Bozo

Introduction: Neurogenic hypertension is associated with unilateral neurovascular compression of the brainstem and cranial nerves V, IX-X, VII, VIII. Causes may include nerve injury, vascular compression, tumors. Symptomatology seems hyperactive dysfunction syndrome of the cranial nerves. In the clinical picture, it can be seen trigeminal neuralgia, vertigo, tinnitus, hemifacial spasm, and in some cases hypertension.Case report: Female patient, 45 years ...

ea0022p793 | Thyroid | ECE2010

Differences in Graves' orbitopathy between hyperthyroid and hypothyroid/euthyroid patients

Beleslin Biljana , Ciric Jasmina , Zarkovic Milos , Stojkovic Mirjana , Ciric Slavica , Knezevic Miroslav , Trbojevic Bozo

Aim: The aim of this study was to compare clinical symptoms and TSH receptor antibodies (TRAb) in Graves orbitopathy (GO) in hyperthyroid patients to those patients with primarily hypothyroid and euthyroid status.Methods: Study group consisted of 54 primarily hyperthyroid (39 female, 14 male, 47±9 years) and 8 primarily hypothyroid and euthyroid patients (5 female, 3 male, 46±14 years). Clinical symptoms and TRAb were assessed. Assessment of th...

ea0020p605 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Hypothalamic–pituitary–adrenal axis in chronic fatigue syndrome

Marina Djordje , Jelic Svetlana , Kostic Nada , Caparevic Zorica , Trbojevic Bozo , Beleslin Biljana , Ilic Sanja , Zarkovic Milos

Background/objectives: The aim of the study was to assess hypothalamic–pituitary–adrenal (HPA) axis in patients with chronic fatigue syndrome (CFS).Design and methods: Twenty-three consecutive patients who fulfilled centers for disease control (CDC) criteria for CFS and twenty healthy controls were included in the study. Low dose ACTH test (1mcg of synthetic adrenocorticotropic hormone Synacthen) and insulin tolerance test (ITT) were done and b...

ea0016p24 | Adrenal | ECE2008

Association of diabetes mellitus and arterial hypertension in adrenal incidentaloma

Zarkovic Milos , Ciric Jasmina , Beleslin Biljana , Savic Slavica , Stojkovic Mirjana , Marina Djordje , Trbojevic Bozo

Background/objectives: The aim of the study was to assess association between diabetes mellitus (DM) and arterial hypertension (AH) in patients with adrenal incidentaloma.Design and methods: One hundred and eleven consecutive patients with incidentally discovered adrenal tumours were included in the study. OGTT was done and 24 h urinary catecholamines were measured. Aldosterone and plasma renine activity (PRA) were determined, and 1 mg dexametasone test ...

ea0016p619 | Reproduction | ECE2008

Intima-media tickness of carotid artery in young women with polycystic ovary syndrome

Stojkovic Mirjana , Civcic Milorad , Beleslin Biljana , Ciric Jasmina , Savic Slavica , Marina Djordje , Trbojevic Bozo , Zarkovic Milos

Background: Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disease that occurs in about 10% of women in reproductive age. Today, PCOS is considered not only reproductive edocrinopathy but also a metabolic disorder associated with long-term health risks, including diabetes mellitus and cardiovascular disease.Objectives: The aim of this study was to evaluate the presense of early vascular demage in normal-weight women with polycystic ovar...

ea0016p732 | Thyroid | ECE2008

Correlations between lipids and thyroid hormones in primary hypothyroidism

Savic Slavica , Trbojevic Bozo , Ciric Jasmina , Beleslin Biljana , Marina Djordje , Stojkovic Mirjana , Zarkovic Milos

The aim of the study was to assess the influence of thyroid hormones on lipid profiles in primary hypothyroidism, in order to determine the most influential one for the clinical follow-up. Study group included 15 subjects (3 male, 12 female, age 46±13 years/mean±S.D.), and total and free T4, total and free T3 and TSH, total, HDL and LDL cholesterol, triglycerides, ApoA, ApoB and Lp(a) were determined. The diagnosis of primary hypothyroidism was based o...

ea0014p370 | (1) | ECE2007

Hypothyroid Graves’ ophthalmopathy: a case report

Ciric Jasmina , Zarkovic Milos , Beleslin Biljana , Stojkovic Mirjana , Savic Slavica , Trbojevic Bozo

Background: Hypothyroid Graves’ ophthalmopathy is a rare condition, present in about 3% of all cases. Since thyroid-stimulating antibodies could be detected in a majority of euthyroid and hypothyroid Graves’ patients, the most probable explanation for unincreased thyroid function is a reduction of tissue capability to response to stimulation.Case report: A 57-yr-old man visited the hospital with signs and symptoms typical of hypothyroidism. Sin...

ea0014p649 | (1) | ECE2007

Insulin levels and lipid profile in lean women with polycystic ovary syndrome

Stojkovic Mirjana , Zarkovic Milos , Ciric Jasmina , Beleslin Biljana , Savic Slavica , Marina Djordje , Trbojevic Bozo , Drezgic Milka

Background: Women with polycystic ovary syndrome (PCOS) appear at increased cardiovascular risk due in part to a dyslipidemia characterized by increased plasma triglyceride and reduced high density lipoprotein (HDL) cholesterol levels. Insulin resistance is one of the features of PCOS and potentially affect lipid metabolism.Objectives: The aim of this study was to compare basal insulin levels and lipid profile in lean women with PCOS with weight matched ...

ea0032p57 | Adrenal cortex | ECE2013

Impact of antihypertensive drugs, sodium intake and potassium plasma concentrations on plasma aldosterone and plasma renin aktivity

Lalic Tijana , Zarkovic Milos , Ciric Jasmina , Beleslin Biljana , Stojkovic Mirjana , Stojanovic Milos , Nisic Tanja , Savic Slavica , Trbojevic Bozo

Introduction: Primary aldosteronism (PA) is a group of disorders which are characterized by inadequate and non-suppressible production of aldosterone. The prevalence of PA is increasing in hypertensive population. The golden standard of screening for primary aldosteronism, determination of aldosterone/plasma renin activity (ARR), is influenced by numerous exogenous and endogenous factors. Testing cannot always be conducted under optimal conditions.Object...