Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep251 | Clinical case reports - Pituitary/Adrenal | ECE2016

21-hydroxylase deficiency presenting as bilateral adrenal masses in the sixth decade of life in a phenotypically male but genetically female patient

Panagiotidi Evgenia , Papadakis Georgios , Manitarou Paraskevi , Tzaves Ioannis , Triantafillou Eleni , Kalaitzidou Styliani , Sapera Aggeliki , Katsoulis Konstantinos , Kaltzidou Victoria , Tertipi Athanasia

Introduction: 21-hydroxylase deficiency (21-OHD) is a common inherited disorder accounting for 90–95% of congenital adrenal hyperplasia (CAH) cases. Some cases may be diagnosed in adulthood after the incidental discovery of adrenal masses on computerized tomography (CT).Case report: A 59-year-old male was investigated for incidentally discovered bilateral adrenal masses in an abdomen CT scan, measuring 5 cm on the right and 8 cm on the left adrenal....

ea0037ep235 | Calcium and Vitamin D metabolism | ECE2015

Vitamin D and seasonal variation among Greek female patients with osteoporosis

Papadakis Georgios , Keramidas Ioannis , Kakava Kassiani , Pappa Theodora , Villiotou Vassiliki , Manitarou Paraskevi , Kalaitzidou Styliani , Triantafillou Eleni , Kaltzidou Victoria , Pappas Anastasios

Background: 25 hydroxy vitamin D (25(OH)D) vitamin levels are positively associated with bone mineral density and season, time of day and sun exposure duration influence its synthesis. Variations in daylight throughout the year and zenith angle, depending on the latitude of residence, influence u.v. solar radiation which is closely related to serum 25(OH)D levels. The aim of this study was to investigate the degree of seasonal variation of 25(OH)D serum levels in a population-...

ea0037ep846 | Thyroid cancer | ECE2015

Association of calcium-stimulated calcitonin values with pathological findings following total thyroidectomy

Papadakis Georgios , Keramidas Ioannis , Triantafillou Eleni , Kanouta Foteini , Pappa Theodora , Kaltzidou Victoria , Tertipi Athanasia , Vecchini Gino , Papadouli Despoina , Pappas Anastasios

Background and objectives: Medullary thyroid carcinoma (MTC) originates from thyroid C-cells and is a calcitonin (CT) secreting tumour with aggressive behaviour. Surgery is recommended in all patients with basal or calcium-stimulated CT values of 100 pg/ml or higher due to the high probability of MTC. The objective of this study was to investigate the utility of calcium stimulation test for CT in order to distinguish MTC from C-cell Hyperplasia (CCH) preoperatively and to exam...

ea0037ep848 | Thyroid cancer | ECE2015

False-positive uptake of radioiodine WBS in a patient with papillary thyroid cancer due to a vertebral hemangioma

Triantafillou Eleni , Kanouta Foteini , Papadakis Georgios , Tzaves Ioannis , Panagiotidi Evgenia , Trivizaki Erasmia , Kaltzidou Victoria , Tertipi Athanasia , Drosou Aspasia , Pappas Anastasios

Introduction: Diagnostic and post-therapy radioiodine whole body scan (WBS) is used in the follow-up of differentiated thyroid carcinoma (DTC) for the detection of local recurrence or remote metastasis. We report a case of false-positive uptake of radioiodine WBS.Case report: A 37-year-old female patient underwent subtotal thyroidectomy for multinodular goitre and histology revealed multifocal papillary thyroid carcinoma, of follicular type with three fo...

ea0063p350 | Thyroid 1 | ECE2019

Outcomes of surgery and radioiodine treatment for neck recurrence in papillary thyroid cancer

Kalaitzidou Styliani , Tampouratzi Dimitra , Papadakis Georgios , Karavasili Chrysi , Triantafillou Eleni , Kanouta Fotini , Sapera Aggeliki , Kotis Michalis , Aravantinou Aggeliki , Roumpidaki Zoi , Dracopoulou Anna , Kaltzidou Victoria , Veniou Irini , Tertipi Athanasia

Background: Persistent/recurrent disease in the neck is frequent in patients with papillary thyroid cancer. The main goal of this study was to evaluate the efficacy of the reoperation and radioiodine (RAI) treatment for persistent/recurrent disease after the initial treatment. Patients and Methods: A total of 30 patients (13 M/17 F) with papillary thyroid cancer were enrolled in this study. Seven cases (23.3%) had an aggressive subtype of papillary carcinoma. All had been subm...

ea0049ep217 | Bone & Osteoporosis | ECE2017

Clinical manifestations and treatment approach in osteogenesis imperfecta

Tampouratzi Dimitra , Kalaitzidou Styliani , Sapera Aggeliki , Kotis Michalis , Kanouta Fotini , Triantafillou Eleni , Kyrimis Taxiarchis , Papadakis Georgios , Drakopoulou Anna , Kaltzidou Victoria , Tertipi Athanasia

Objectives: Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affects the bones. The underlying mechanism is usually a disorder of connective tissue due to lack of type I collagen. Usually, the disease is due to mutations in the COL1A1 or COL1A2 genes. The disease is inherited in an autosomal dominant manner or occurs via a de novo mutation. There are eight types of the disease. Type I is the most common and the least sever type and is due to mutation in...

ea0041ep1106 | Thyroid cancer | ECE2016

Biochemical effects of levothyroxine withdrawal in patients with differentiated thyroid cancer

Papadakis Georgios , Kalaitzidou Styliani , Triantafillou Eleni , Kakava Kassiani , Drosou Aspasia , Sapera Aggeliki , Dogkas Nikolaos , Pappa Theodora , Kaltzidou Victoria , Villiotou Vassiliki , Tertipi Athanasia

Background: Many patients with differentiated thyroid cancer (DTC) are treated with radiodine (I-131) after thyroidectomy, while they are hypothyroid and all are submitted to withdrawal of LT4 periodically for the evaluation of their disease. Among the tests used for follow-up is serum thyroglobulin (Tg) as a tumor marker, and occasionally, total body scan with I-131. Maximal sensitivity of the aforementioned tests is established in the hypothyroid state, under elevated thyrot...

ea0041ep1129 | Thyroid cancer | ECE2016

The diagnostic value of FNAB for early diagnosis of thyroid cancer: a Greek center experience

Triantafillou Eleni , Papadakis Georgios , Manitarou Paraskevi , Panagiotidi Evgenia , Kanouta Fotini , Drosou Aspasia , Kaldrymidis Philippos , Kaltzidou Victoria , Tsouma Eleni , Alexiadou Anastasia , Plyta Styliani , Tertipi Athanasia

Introduction: Fine needle aspiration biopsy (FNAB) is the initial investigation of choice for thyroid nodules.Methods: A total of 563 patients (106 males/457 females) underwent FNAB for the same number of thyroid nodules. Their mean age was 56.1±14.1 years. We correlated the demographic profile (age and gender) and sonographic features of these nodules with the FNAB outcome. The Bethesda system for reporting thyroid cytopathology was used.<p cla...

ea0037ep847 | Thyroid cancer | ECE2015

Primary thyroid lymphoma: a heterogeneous disease and presentation of two different cases

Triantafillou Eleni , Papadakis Georgios , Keramidas Ioannis , Moustakas Konstantinos , Tsakonas Georgios , Manitarou Paraskevi , Drosou Aspasia , Tzaida Olympia , Tertipi Athanasia , Tzaves Ioannis , Megalakaki Aikaterini , Pappas Anastasios

Background: Primary thyroid lymphoma (PTL) is a rare thyroid malignancy. Nevertheless, it frequently presents diagnostic and therapeutic challenges. We describe two patients with PTL with different clinical presentation/clinical picture and outcome.Patients and methods: Two female patients underwent total thyroidectomy, the first, a 67-year-old female patient, because of nodular goitre and the second, a 79-year-old female patient, because of a large, pai...

ea0056p632 | Clinical case reports - Thyroid/Others | ECE2018

Patient with neurofibromatosis type 1 and follicular thyroid cancer

Kanouta Fotini , Kalaitzidou Styliani , Triantafillou Eleni , Drousou Aspasia , Kyrimis Taxiarchis , Tampouratzi Dimitra , Kotis Michalis , Papadakis Georgios , Kaltzidou Victoria , Veniou Eirini , Drakopoulou Anna , Karavasili Chrysa , Mastorakos Georgios , Tertipi Athanasia

Objectives: Neurofibromatosis type 1 (NF1) is an autosomal, dominant, genetic disorder. The genetic lesion in neurofibromatosis type 1 is located at locus 17q11.2 that harbors the neurofibromin gene. Patients have 3-4 times higher possibility to develop malignancies relative to the general population. The endocrine manifestations of neurofibromatosis include precocious puberty, short stature, osteoporosis and pheochromocytoma. We present a patient with neurofibromatosis type 1...