Searchable abstracts of presentations at key conferences in endocrinology

ea0029p221 | Calcium & Vitamin D metabolism | ICEECE2012

Perioperative management difficulties in parathyroidectomy for primary vs secondary and tertiary hyperparathyroidism

Corneci C. , Stanescu B. , Trifanescu R. , Neacsu E. , Poiana C.

Background: In patients with hyperparathyroidism, parathyroidectomy is the only curative therapy. Anesthetic management differs function of etiology (primary vs secondary or tertiary hyperparathyroidism) and surgical technique (minimally invasive or classic parathyroidectomy).Aim: To evaluate peri-operative management in parathyroidectomy for hyperparathyroidism of various etiologies, in a tertiary center.Patients and methods: Two ...

ea0029p438 | Clinical case reports - Thyroid/Others | ICEECE2012

Thyrotoxicosis-associated acute myocardial infarction and ventricular fibrillation in a patient with normal epicardial coronary arteries

Trifanescu R. , Bicescu G. , Radulescu L. , Poiana C.

Introduction: Hyperthyroidism-associated myocardial infarction with normal epicardial coronary arteries on angiogram is seldom reported.Case report: A 61-year-old Caucasian man, resident in an iodine sufficient area, presented with chest pain in the emergency unit. ECG revealed inferolateral myocardial infarction with ST-segment elevation. Soon after admission, the patients developed collapse due to primary ventricular fibrillation, requiring defibrillat...

ea0026p638 | Clinical case reports | ECE2011

Hyponatremic coma with seizures as onset of isolated ACTH deficiency

Trifanescu R A , Stoicescu A , Caragheorgheopol A , Hortopan D , Coculescu Mihail

Introduction: Isolated acquired ACTH deficiency is rare; it may be due to hypophysitis and association with other autoimmune diseases was reported.Case report: E.L, female, aged 34, was diagnosed with primary autoimmune hypothyroidism and premature ovarian failure; levothyroxine and estroprogestins were administered. Suddenly, the patient developed vomiting, shivers without fever and soon coma installed, with tonic-clonic seizures. There was no history o...

ea0009p98 | Endocrine tumours and neoplasia | BES2005

What is the final outcome in patients with macroprolactinoma resistant to dopamine agonists?

Trifanescu R , Karavitaki N , Coculescu M , Turner H , Wass J

BACKGROUND: Dopamine agonists are the treatment of choice in macroprolactinomas. A number of these tumours do not respond to the commonly used doses. In such cases the outcome after alternative approaches has not been clarified.AIM: To assess the response of macroprolactinomas to bromocriptine (BRC) or cabergoline (CAB) and the result of further interventions in resistant cases.PATIENTS AND METHODS: All records of the patients pres...

ea0029p965 | Female Reproduction | ICEECE2012

Sertoli cells ovarian tumor- an ovarian incidentaloma?

Poiana C. , Carsote M. , Trifanescu R. , Ene C. , Neamtu C. , Iosif C. , Terzea D.

Introduction: Infertility investigations include uterine┬ľovarian ultrasound. The incidental finding of a tumor in a young female might associate a potential severe prognosis in otherwise completely asymptomatic patient.Aim: We present a case of a young female with an accidentally discovered ovarian tumor.Case report: S.M. 35-year female patient is admitted for infertility. Her family and personal medical history is irrelevant....

ea0029p1510 | Pituitary Clinical | ICEECE2012

Follow up of pituitary incidentaloma: a study in 140 patients

Poiana C. , Carsote M. , Trifanescu R. , Danciulescu-Miulescu R. , Musat M. , Hortopan D. , Dumitrascu A.

Introduction: Pituitary incidentaloma is a relatively frequent imagistic finding. Since no therapy is necessary, the follow up protocol is the most important in patients┬ĺ approach.Aim: We present a study in patients diagnosed with pituitary incidentaloma, admitted in I.Parhon, Bucharest, between 1999 and 2011.Patients and method: This is a retrospective study in 140 patients, diagnosed with pituitary incidentaloma based on CT ...

ea0026p287 | Pituitary | ECE2011

Tumor size and parasellar extension influence on macroprolactinomas’ outcome

Trifanescu R A , Mihaila V , Serban A , Hortopan D , Dumitrascu A , Caragheorgheopol A , Coculescu M

Introduction: Parasellar extension of macroprolactinomas defined on imaging criteria was reported to be an independent predictor of hormonal resistance to dopamine agonists (DA).Methods: Two hundred and twelve patients with macroprolactinomas (87 M/125 F), treated with DA for 5 years median period; prolactin (fluoroimmunoassay or chemiluminescence), CT scan and/or MRI with contrast agents were performed; maximum diameter evolution was reported.<p cla...

ea0009p105 | Endocrine tumours and neoplasia | BES2005

Clinically mute adrenal tumours - study of 63 cases

Gheorghiu M , Hortopan D , Dumitrascu A , Stefanescu A , Trifanescu R , Niculescu D , Coculescu M

Background: There is a large agreement that most of the incidentally discovered, clinically mute adrenal masses are incidentalomas - non-functioning tumours, which have to be explored in order to differentiate the adrenal carcinoma.Material and methods: We studied the prevalence and characteristics of clinically mute adrenal tumours and the evolution of adrenal incidentalomas, with the approval of the local Ethical Committee, in 123 patients with adrenal...