Searchable abstracts of presentations at key conferences in endocrinology

ea0099p397 | Late-Breaking | ECE2024

Reversible and late-onset adrenal insufficiency in survivors of COVID19: results from a 24-month longitudinal study

Sahoo Saroj , Menon Jayakrishnan , Tripathy Nidhi , Nayak Monalisa , Yadav Subhash

Objective: The SARS-CoV-2 requires angiotensin-converting enzyme 2 (ACE2) receptor and transmembrane serine protease 2 (TMPRSS2) for gaining entry inside the cells (1). In humans, ACE2 and TMPRSS2 mRNAs are expressed in several endocrine glands, including the hypothalamus, pituitary, and adrenal cortex (2). Thus, it is possible that patients with COVID19 may have hypothalamic-pituitary-adrenal (HPA) axis dysfunction both during acute COVID19 and/or following recovery from COVI...