Searchable abstracts of presentations at key conferences in endocrinology

ea0014p544 | (1) | ECE2007

Topoisomerase II alpha expression in pituitary tumours – preliminary results

Trofimiuk Malgorzata , Adamek Dariusz , Czepko Ryszard , Sokolowski Grzegorz , Huszno Bohdan

Introduction: Topoisomerase II alpha is regarded as the important marker of cellular proliferation. Pituitary tumours are usually benign, but some of them are characterized by rapid growth, high recurrence rate and local invasiveness. Proliferation marker Ki-67 most commonly used in pituitary tumours is not entirely reliable as the indicator of the aggressive growth of the lesion. Topoisomerase II alpha expression assessment may be a valuable tool for identification such pitui...

ea0022p783 | Thyroid | ECE2010

Changing trends in the incidence of thyroid carcinoma in a single clinical centre

Anielski Ryszard , Cichon Stanislaw , Trofimiuk Malgorzata , Orlicki Pawel , Hubalewska-Dydejczyk Alicja

Introduction: The incidence of the thyroid carcinoma (TC) is relatively low, although its increase has been observed in the last 20 years.Aim: A comparative clinical and epidemiological analysis of two cohorts of patients surgically treated for the thyroid diseases in the Endocrine Surgery Department in Cracow during two five-year periods: 1982–1986 and 2000–2005.Material and methods: Two subsets of patients, who underwen...

ea0022p849 | Thyroid | ECE2010

The thyroid volume reference values for Polish children

Szybinski Zbigniew , Trofimiuk Malgorzata , Buziak-Bereza Monika , Kieltyka Agnieszka , Sokolowski Grzegorz , Hubalewska-Dydejczyk Alicja

Measuring of goiter by ultrasonography is one of the generally accepted methods for iodine nutrition assessment. Discordance between previously used and lately proposed thyroid volume (TV) reference values (TVRV) is the subject of discussion and makes it difficult to properly interpret the effects of iodine prophylaxis.Aim: To establish TVRV for Polish schoolchildren population.Material and methods: 2903 schoolchildren aged 6–...

ea0016p407 | Neuroendocrinology | ECE2008

Pituitary abscess: a case report

Darczuk Andrzej , Trofimiuk Malgorzata , Gil Justyna , Hubalewska-Dydejczyk Alicja , Mnich Wlodzimierz , Adamek Dariusz

Pituitary abscess is a very rare entity, only 200 cases (mostly the complication of the pituitary surgery) has been described so far.We want to present the case of pituitary abscess arising from Rathke’s cyst.Case report: Seventy-years-old female treated due to clinical depression, was admitted to the Endocrinology Department because of profound hyponatremia (serum Natrium 119 mmol/l). She was diagnosed with plurihormonal ante...

ea0014p151 | (1) | ECE2007

Frequency of occurence of MEN1 syndrome in patients admitted with primary hyperthyroidism

Baldys-Waligorska Agata , Sokolowski Grzegorz , Trofimiuk Malgorzata , Golkowski Filip , Huszno Bohdan

Background: Primary hyperparathyroidism (HPT) is the most common endocrinopathy in MEN1 and usually its first clinical manifestation. Yet MEN1 is a rare disease, representing only 2–4% of all cases of HTP. We studied the frequency of MEN1 syndrome in HPT patients admitted to our Department.Methods: In a retrospective analysis of 84 suspected HPT patients hospitalized in 1999–2006, case reports of 11 patients with suspected MEN1 were analysed. M...

ea0014p543 | (1) | ECE2007

Meningiomas in patients diagnosed with acromegaly: the report of two cases

Trofimiuk Malgorzata , Adamek Dariusz , Czepko Ryszard , Sokolowski Grzegorz , Baldys-Waligorska Agata , Huszno Bohdan

Introduction: Only several cases of co-existing meningiomas and pituitary tumours secreting growth hormone (GH) have been described so far in patients not treated previously with irradiation.Aim: The aim of the study was to describe two cases of co-occurrence of acromegaly and meningioma and to discuss their relationship.Case reports: Case 1. 52-year old female complained of visual disturbances. She was diagnosed with pituitary mic...

ea0020p119 | Thyroid | ECE2009

Assessment of the thyroid hormone’s profile during pregnancy

Hubalewska-Dydejczyk Alicja , Kostecka-Matyja Marta , Pach Dorota , Buziak-Bereza Monika , Trofimiuk Malgorzata , Gil Justyna , Polak Edyta

Introduction: In accordance with a rising number of pregnant women with thyroid gland dysfunctions, The Thyroid Gland’s Disorders Outpatient Clinic for Pregnant Women has started its activity in our Endocrinology Department in January 2008. Patients with or without thyroid gland dysfunction in history have been under medical care.During pregnancy thyroid gland is prone to the number of physiological changes, which cause difficulties in the interpret...

ea0020p198 | Endocrine tumours and neoplasia | ECE2009

Gastric neuroendocrine tumors – new diagnostic and therapeutic approach

Hubalewska-Dydejczyk Alicja , Gilis-Januszewska Aleksandra , Sowa-Staszczak Anna , Pach Dorota , Trofimiuk Malgorzata , Tomaszczuk Monika , Kulig Jan

The incidence of gastric neuroendocrine tumors (GNT) is increasing, what can be explained by the increased detection caused by the common use of the endoscopy and the pervasive use of acid suppressive therapy leading to enterochromatofine like cells proliferation. There are numerous new diagnostic/therapeutic GNT methods in use like: EUS, SRS, somatostatin therapy and 90Y/177Lu-DOTA-TATE radiotherapy.Materials and methods: In 1998–2008 37 patients w...

ea0016p323 | Endocrine tumours | ECE2008

Neuroendocrine tumours (NETs): one centre experience

Hubalewska-Dydejczyk Alicja , Trofimiuk Malgorzata , Sowa-Staszczak Anna , Szybinski Piotr , Kulig Jan , Pach Dorota , Gilis-Januszewska Aleksandra , Huszno Bohdan

Background: NETs are rare tumours arising from dispersed neuroendocrine system. Nevertheless, their estimated prevalence increased lately, mostly due to progress in imaging, biochemical and histopathological diagnostics.The aim of the study was to present the characteristics of the NETs patient surveyed in our Endocrinology Department since 2000.Material and methods: One hundred and fifty-eight patients (males – 42.4%, females...

ea0014p172 | (1) | ECE2007

Diagnosis and treatment of the ACTH-secreting neuroendocrine pancreatic tumors

Aleksandra Gilis-Januszewska , Alicja Hubalewska-Dydejczyk , Malgorzata Trofimiuk , Dorota Pach , Magdalena Szurkowska , Monika Buziak-Bereza , Elwira Mazurek , Bohdan Huszno

Introduction: Neuroendocrine tumors secreting ACTH are a rare cause of Cushing’s syndrome.Diagnostic and therapeutical difficiulties might be caused due to different clinical picture of of neuroendocrine tumors.Patients, diagnostic and therapeutic approach: During 2004–2005 2 female patients 32-years old AL and 67-years old ZS were hospitalized in Endocrinology Department due to severe hypercorticism signs and symptoms. I...