Searchable abstracts of presentations at key conferences in endocrinology

ea0026p586 | Clinical case reports | ECE2011

A case report of macronodular adrenal hyperplasia with combined cortisol and aldosterone oversecretion in response to β-adrenergic and vasopressin stimuli

Papanastasiou L , Pappa T , Tsiavos V , Tseniklidi E , Prevoli A , Tsounas P , Markou A , Piaditis G

Introduction: Adrenocorticotropin (ACTH)-independent macronodular adrenal hyperplasia (AIMAH) is a rare cause of CushingÂ’s syndrome, commonly involving the aberrant expression of several membrane-bound adrenal receptors. Recent studies have investigated whether the latter is also implicated in the renin-independent aldosterone secretion of hyperaldosteronism cases.Case report: A 35-year-old man presented to our department for evaluation of new-onset...

ea0029p58 | Adrenal cortex | ICEECE2012

Treatment with mineralocorticoid receptor antagonists in ‘subclinical’ cases with adrenal adenomas and autonomous aldosterone secretion

Papanastasiou L. , Pappa T. , Tsounas P. , Tsiavos V. , Markou A. , Tseniklidi E. , Anastasakou M. , Fountoulakis S. , Prevoli A. , Piaditis G.

Introduction: Patients with adrenal adenomas appear to exhibit an appreciable prevalence of autonomous aldosterone secretion (AAS). Our aim was to evaluate the anti-hypertensive effect of targeted therapy with mineralocorticoid receptor (MR) antagonists in AAS patients.Patients and methods: We studied 60 hypertensive patients, 21 males and 39 females, harboring an adrenal adenoma with AAS. All patients were receiving combination of anti-hypertensive trea...