Searchable abstracts of presentations at key conferences in endocrinology

ea0091wa14 | Workshop A: Disorders of the hypothalamus and pituitary | SFEEU2023

Pituitary macroprolactinoma with apoplexy following commencement of GH replacement therapy

McEvoy Robert , Tuthill Antoinette

A 19-year-old man attended his optician with an 18-month history of decreased visual acuity. Formal visual field testing revealed significant bitemporal hemianopia. On further questioning in hospital, his voice had deepened only 6 months previously. He had no facial hair. He had no difficulty with erections or libido. He had felt fatigued for months, but had no headaches, weight loss or postural dizziness. There was no history of galactorrhoea, gynaecomastia, nocturia, or exce...

ea0013p168 | Diabetes, metabolism and cardiovascular | SFEBES2007

Usefulness of the body image assessment in obesity scale in a UK clinic population

Tuthill Antoinette , Finer Nicholas

Aim: We aimed to evaluate the usefulness of the Body Image Assessment in Obesity (BIA-O) scale in a UK obesity clinic population by assessing its performance in individuals with a Body Mass Index (BMI) above 50 Kg/m2, evaluating whether obese subjects selected achievable ‘reasonable’ body sizes, and comparing the relationship between body dissatisfaction on the Eating Disorder Inventory-2 (EDI-2) and BIA-O.Methods: Subjects attending...

ea0021p68 | Clinical practice/governance and case reports | SFEBES2009

Low sodium and neurological findings: consider the diagnosis

Brassill Mary Jane , Tuthill Antoinette

A 61-year-old gentleman, with a background of chronic schizophrenia, presented with hyponatraemia in 2008 and was diagnosed with Addison’s disease. He had two previous admissions with hyponatraemia in 2002 and 2006. During his first admission his hyponatraemia was attributed to volume depletion secondary to vomiting, and he responded to fluid resuscitation. On the second occasion, SIADH (syndrome of inappropriate antidiuretic hormone) was diagnosed secondary to antipsycho...

ea0034p405 | Thyroid | SFEBES2014

Scalp metastasis in follicular thyroid cancer: an atypical consequence

Hannon Anne Marie , O'Brien Frank , Fitzgerald Deirdre , Tuthill Antoinette

Follicular thyroid cancer is the second most common cause of thyroid carcinoma. Metastasis occurs in 10–15% of cases. Typical sites of metastasis include bone and lungs, scalp metastasis are rare, with <50 cases reported. We describe two such cases.A retrospective chart review was performed on these patients, examining presentation, treatment and subsequent outcomes.Patient 1. An abnormal lesion was noted on a routine ches...

ea0025p80 | Clinical biochemistry | SFEBES2011

Targets for improvement of care for thyroid carcinoma patients in the multidisciplinary setting

Lowney Aoife , Crowley Rachel , O'Halloran Domhnall , Tuthill Antoinette

The British Thyroid Association recommends that a specialist multidisciplinary team (MDT) is responsible for thyroid cancer management. In accordance with this recommendation, a team was formed to manage thyroid carcinoma in a tertiary referral centre. The team included endocrinology, general surgery, ENT, cytology, radiology and radiation oncology consultants.This audit was performed to assess management of thyroid carcinoma before the establishment of ...

ea0021p11 | Bone | SFEBES2009

Assessment of vitamin D status in patients with primary hyperparathyroidism

Brassill Mary Jane , Adrees Muhammed , O'Mullane John , Tuthill Antoinette

Vitamin D insufficiency is common in the Irish population. Patients with primary hyperparathyroidism (PHPT) and co-existing vitamin D insufficiency have higher PTH levels, increased bone turnover and increased risk of postoperative hypocalcaemia. The 3rd International Workshop on PHPT recommended measurement of serum 25-OH Vitamin D in all patients with PHPT, and treatment where required to maintain 25-OH Vitamin D >50 nmol/l. Our study aimed to assess vitamin D status in ...

ea0021p206 | Endocrine tumours and neoplasia | SFEBES2009

Case report: multiple endocrine neoplasia type 2a and hereditary haemorrhagic telangiectasia presenting consecutively in a single patient

Hussein Omer , Crowley Rachel , Sheahan Patrick , Brady Adrian , Tuthill Antoinette

Multiple endocrine neoplasia type 2a (MEN 2a) is an autosomal dominant disorder with an incidence of ~1 in 30 000 of the population. It is characterized by medullary thyroid cancer (MTC), benign or malignant phaeochromocytomas, and parathyroid hyperplasia or tumours.Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome), is also an autosomal dominant disorder; this condition occurs with an incidence of ~1–2 per 100 000 of the population....

ea0025p341 | Thyroid | SFEBES2011

What is the influence of rheumatologic conditions on response to medical therapy of Graves’ disease?

Gulati Kavita , O'Sullivan Miriam , Molloy Michael , Stapleton Mary , Harney Sinead , O'Halloran John , Ryan John , Tuthill Antoinette

Anecdotal reports suggest that management of Graves’ disease (GD) is more challenging in patients with concomitant autoimmune disease, however there are few studies evaluating this premise and thus no satisfactory evidence base to guide clinicians. We aimed to identify the impact of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) on treatment outcomes of GD.We identified all GD patients (n=265) who attended endocrinology clin...

ea0021p7 | Bone | SFEBES2009

Osteoporosis in a young cohort: aetiology and gender differences in referral for DXA

Ryan Stephen , Crowley Rachel K , Chavrimootoo Shawn , Harney Sinead , Tuthill Antoinette

In young patients osteoporosis is associated with endocrine and inflammatory conditions. Early identification of osteoporosis may reduce later morbidity.We aimed to establish the aetiology of low bone mineral density (LBMD) in young patients at our centre. We identified risk factors and impact of gender on BMD in a young at-risk cohort.All patients between 20 and 55 years old who underwent DXA scan between 2004 and 2009 were identi...

ea0013p148 | Diabetes, metabolism and cardiovascular | SFEBES2007

A prospective randomised controlled trial of lifestyle intervention on quality of life and cardiovascular risk score in patients with obesity and type 2 diabetes

Tuthill Antoinette , Quinn Alison , McColgan Donna , McKenna Malachi , O’Shea Donal , Joseph McKenna T

Aim: To evaluate whether a prospective randomised controlled trial of intensive lifestyle intervention delivered on a monthly out-patient basis can result in reduced cardiovascular risk, and improved quality of life in obese patients with type 2 diabetes.Patients and Methods: Patients were recruited from diabetes out-patient clinics. All subjects underwent a treadmill exercise test to assess eligibility before randomization. Subjects with a negative exer...