Searchable abstracts of presentations at key conferences in endocrinology

ea0022p89 | Bone/Calcium | ECE2010

Comparison of alendronate and raloxifene as a medical treatment option in patients with primary hyperparathyroidism

Akbaba Gulhan , Isik Serhat , Tutuncu Yasemin , Ozuguz Ufuk , Berker Dilek , Guler Serdar

Introduction: Primary hyperparathyroidism (pHPT) is the most frequent cause of hypercalcemia in ambulatory patients. Most persons have no symptoms, and pHPT usually is diagnosed after an elevated serum calcium (Ca2+) level is found incidentally. Parathyroidectomy is the definitive treatment for pHPT. There have been several different approaches to the medical management of pHPT. Our aim in this study is to compare alendronate sodium (ALN) and raloxifene (RLX) effici...

ea0022p664 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Comparison of efficacy of cabergoline and bromocriptine retrospectively in patients with hyperprolactinemia

Isik Serhat , Berker Dilek , Tutuncu Yasemin , Ozuguz Ufuk , Arduc Ayse , Akbaba Gulhan , Aydin Yusuf , Guler Serdar

Objective: Patients with hyperprolactinemia who require medical therapy are typically treated with dopamine agonists (DA). In most cases, medical therapy with DA normalizes the level of prolactin (PRL), restores gonadal function and fertility, and substantially reduces the size of the tumor. Here, we aimed to compare the efficacy of cabergoline (CAB) and bromocriptine (BRC) in hyperprolactinemic patients retrospectively.Methods: Retrospective analysis of...

ea0022p666 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

comparison of octreotide LAR and lanreotide autogel treatments in post-operative medical treatment of acromegaly

Tutuncu Yasemin , Berker Dilek , Isik Serhat , Ozuguz Ufuk , Akbaba Gulhan , Kucukler Ferit Kerim , Guler Serdar

Objective: Long acting somatostatin analogs commonly used as adjuvant treatment of acromegalic patients after noncurative surgery. We aimed to compare the efficacy of octreotide LAR (OCT) and lanreotide Autogel (LAN) in acromegalic patients.Methods: Sixty-eight patients that cure could not be achieved by transsfenoidal endoscopic or microscopic pituitary surgery between 2003 and 2009 were retrospectively analyzed (25 men and 43 women; mean age 41.1±...

ea0020p84 | Thyroid | ECE2009

Clinicopathologic features of incidental and nonincidental papillary thyroid microcarcinoma

Ozuguz Ufuk , Berker Dilek , Aydin Yusuf , Isik Serhat , Tutuncu Yasemin , Delibasi Tuncay , Guler Serdar

Objective: Most of the papillary thyroid microcarcinomas (PTMC) are incidentally discovered in pathological examination after the surgery of benign thyroid disorders. The purpose of the present study was to evaluate clinicopathologic features of incidental and nonincidental PTMC.Material and methods: We evaluated 56 patients with PTMC between 2003 and 2008 at the Division of Endocrinology of the Numune Training and Research Hospital. We analyzed the tumo...

ea0020p436 | Obesity and Metabolism | ECE2009

Association between visceral fat and cardiovascular disease risk factors

Berker Dilek , Aydin Yusuf , Isik Serhat , Tutuncu Yasemin , Pasaoglu Lale , Delibasi Tuncay , Guler Serdar

Objective: We designed this study to evaluate whether visceral fat area (VFA), and subcutaneous fat area (SFA) are associated with atherosclerotic parameters in obese and non-obese subjects.Material and methods: Of 104 healthy volunteers were recruited for the study. Participitants were divided into two groups according to their body mass index (BMI). Group 1 has a BMI of <25 kg/m2 (n=31) and the BMI of the group 2 was ≥25 kg/...

ea0020p603 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Prevalence of colonic polyps in acromegalic patients and relationship between glycemic status

Tutuncu Yasemin , Aydin Yusuf , Berker Dilek , Isik Serhat , Akcil Gulhan , Yuksel Osman , Delibasi Tuncay , Guler Serdar

Objective: Acromegaly is associated with an increased prevalence of colonic polyps. The aim of this study was to evaluate the prevalence of colonic polyps in acromegalic subjects, and also whether there is a relationship between insulin-like growth factor 1 (IGF-1), growth hormon (GH), fasting insulin plasma levels and the presence of polyps.Material and methods: Fifty-four consecutive acromegalic patients and 45 IBS patients were enrolled to study betwe...

ea0016p52 | Adrenal | ECE2008

Relation between serum adiponectin level, subclinical Cushing's syndrome and non-functional adrenal incidentaloma

Unal Asli Dogruk , Ayturk Semra , Kemal Yasemin , Tutuncu Neslihan Bascil , Demirag Nilgun Guvener

In this study we compared plasma adiponectin levels between patients with non-functional adrenal incidentaloma and subclinical Cushing’s syndrome. Our aims were to determine whether there was any difference of plasma adiponectin levels, any relation between cardiovasculer risk factors and to investigate the importance of adiponectin levels in subclinical Cushing’s syndrome patients according to non-functional adrenal incidentaloma patients. The patients referred from...

ea0016p690 | Thyroid | ECE2008

Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease

Demirer Asli Nar , Kemal Yasemin , Tutuncu Neslihan Bascil , Gursoy Alptekin , Demirag Nilgun Guvener

Objective: Our aim was to determine the prevalence and clinicopathological characteristics of thyroid cancers in the dialysis population and to evaluate potential risk factors.Design: We performed a retrospective analysis of our end-stage renal disease (ESRD) patients on dialysis and thyroidectomized patients without ESRD (2000–2006). Then we compared the data of thyroid cancer patients on dialysis (n=9) with the data of patients who had hist...

ea0014p34 | (1) | ECE2007

Ambulatory blood pressure reduction after rosiglitazone treatment in normotensive type 2 diabetic patients

Kemal Yasemin , Tutuncu Neslihan , Guvener Nilgun , Unal Asli , Atar Ilyas , Muderrisoglu Haldun

Objective: The thiazolidinediones are new and potentially useful developments in the treatment of type 2 diabetes and impaired glucose tolerance. We tested the effects of the thiazolidinedione, rosiglitazone on blood pressure in normotensive type 2 diabetes.Methods: After receiving approval from the local ethics committee, 25 normotensive diabetic patients were were enrolled to the study. Before the rosiglitazone treatment we measured plasma glucose, HbA...

ea0049ep56 | Adrenal cortex (to include Cushing's) | ECE2017

The frequency of incidental liver and renal masses in patients with adrenal incidentalomas

Nasiroglu Imga Narin , Tutuncu Yasemin , Unal Mustafa , Tuna Mazhar Muslum , Aycicek Bercem , Isik Serhat , Berker Dilek , Guler Serdar

Purpose: Adrenal incidentalomas (AIs) are adrenal masses, which are found on imaging studies not performed related to an adrenal problem. Hepatic incidental masses and renal incidental masses are usually seen in abdominal imaging methods. We aim to investigate the frequency and the kind of hepatic and renal incidental masses in patients with AIs.Methods: Retrospective evaluation of 381 (245 female and 136 male) AI patients and 285 (168 female and 117 mal...