Endocrine Abstracts

Introduction: Sheehan’s sydrome was known varying degrees of hypopituitarism due to postpartum ischemic necrosis by different etiologies. We report two case who are presented with pancytopenia which is unusual and rarely observed an important clinical finding associated with Sheehan’s syndrome.Case 1: A 57-year-old woman has complaints of malaise, fatigue, and dyspnea without lymphadenopatia and hepatosplenomagaly. She had excessive bleeding af...

Smoking is a modifyable risk factor in the incidence of impaired glucose tolerance and type 2 diabetes, but the data concerning the effect of smoking on the course of type 2 diabetes is limited. In this study, we aimed to investigate a possible relationship between smoking and the need of insulin therapy in patients with type 2 diabetes. 470 patients with type 2 diabetes were assessed for smoking habitus, marital and educational status, duration of diabetes, duration of insuli...

Aim: Overt/subclinic hypothyroidism and hyperthyroidism are known to be associated with cardiovascular risks. There have been no studies evaluating the relationship between nodule presence and arterial stiffness in individuals with euthyroid nodular goitre. Our aim in this study is to demonstrate whether nodule presence and nodule stiffness affect arterial stiffness in individuals with euthyroid nodular goitre by using pulse wave analysis (PWA).Materials...

Evaluation of Laboratory Findings of Primary Hyperparathyroidism in Geriatric PatientsBackground: Primary hyperparathyroidism (PHPT) is an endocrine disease characterized by excessive secretion of parathormone (PTH) from one or more parathyroid glands. In recent studies, it has been reported that the PHPT clinic has turned into a largely asymptomatic disease in recent years. There are few studies on the effect of aging on laboratory find...

Introduction: Exosomes are nanoparticles containing bioactive molecules reflecting individual physiological status, regulating metabolism, and repairing damaged tissues. Exosomes are extracellular vesicles with nano-sized features (30-150 nm) involved in cell-to-cell communication and maintaining homeostasis. The function of exosomes is different according to their cargo and they can contain lipids, proteins and nucleic acids. Exosomes originating from mammalian cells as well ...

Introduction: In recent years, it is thought that cardiovascular risk is increased in patients with nonfunctional adrenal insidentaloma (NFAI). There are not enough studies in the literature that evaluating this condition in patients with NFAI who don’t have traditional cardiovascular risk factors. The aim of our study is to determine peripheral and central blood pressures and arterial stiffness in patients with NFAI who don’t have traditional risk factors and autono...

Introduction: Thyrotropinomas are usually considered when the TSH level is inappropriately elevated or normal in a hyperthyroid patient with increased serum T4 levels, regardless of the presence of visible tumor on imaging. The prevalence of these adenomas, which account for 0.5–3% of all pituitary tumors has been estimated to be around one case per million. Most thyrotroph adenomas are large and invasive at diagnosis, and present with signs and symptoms of an ...

Background and aim: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder in women with reproductive age. Nodular goiter and autoimmune thyroid disease (AITD) are frequently seen endocrinological abnormalities. The aim of this study was to identify the prevalence of AITD and nodular goiter in PCOS patients and investigate whether PCOS related hormones and metabolic factors affect these thyroid disorders.Methods: Ninety-seven with ...

Introduction: The neuropathies are one of the most common complications seen in diabetes, affecting up to 50% of diabetic patients. Isolated or combined paralysis of 3rd, 4th and 6th cranial nerve can be seen.Case presentation: Sixty-six-year-old male patient was admitted to the neurology department with the complaints of diplopia persisting for 15 days. Cranial images revealed no abnormal findings. Patient was directed to internal medicine clinic due to...

Aim: In our study we aimed to investigate neutrophil/lymphocyte (N/L) ratio, variations in leukocytes and leukocyte subtypes and relationship between N/L ratio and insulin resistance (IR) in obesity.Material and methods: In this study 250 obese patients data were scanned retrospectively and 96 patients that are convenient to inclusion criteria and has complete file information were included in the study. Forty healthy individual with similar age and sex ...