Searchable abstracts of presentations at key conferences in endocrinology

ea0051p007 | Bone | BSPED2017

Early hypocalcaemia in neonates associated with vitamin D deficiency

Reed John , Upadrasta Swathi

Neonatal hypocalcaemia (NH) is a well described phenomena with values of 2–2.25 mmol/l seen at 24 h of age after the cessation of transfer of transplancental calcium. Levels then increase to normal by 2 weeks of life. Calcium levels below 2.0 mmol/l in infants >1.5 kg is considered to be pathological hypocalcaemia. The role of vitamin D in NH is unclear and not well studied in both neonate and mother.Aim: To present the features of neonates with...

ea0058p043 | Thyroid | BSPED2018

Audit of management of neonates born to mothers with thyroid disorders

Tamhankar Priti , Upadrasta Swathi

Introduction: Maternal thyroid disorders influence neonatal thyroid status. Neonatal thyrotoxicosis (NT) is a potentially fatal condition with high risk in those with clinical signs, high or unknown maternal thyroid receptor antibody (TRAb) status and where mother is clinically hyperthyroid or on treatment. The aim of post-natal management of these babies is to identify those at risk of NT and monitor them. There is, however, no available national or international consensus.</...

ea0039ep44 | Diabetes | BSPED2015

Increased insulin requirement may contribute to higher BMI in children and young people with type 1 diabetes mellitus

Upadrasta Swathi , Finnigan Lynne , Connellan Linda , Ng Sze May

Background: Previous studies have reported that increased BMI and increase in insulin requirement are associated with more rapid disease progression following diagnosis in type 1 diabetes mellitus (T1DM). The recent UK National Paediatric Diabetes Audit (NPDA) 2013/14 reported that 37% of 0–11 year old children and 44% of 12 years and older children are currently overweight or obese.Objective: Our objective was to evaluate factors associated with in...

ea0039ep75 | Gonadal, DSD and reproduction | BSPED2015

Intravaginal foreign body should be excluded in prepubertal cyclical vaginal bleeding without other evidence of precocious puberty

Upadrasta Swathi , Watson Lauren , Natarajan Anuja , Ng Sze May

Background: Isolated prepubertal vaginal bleeding can be secondary to various causes including Mullerian cyst, papilloma, foreign body and prepubertal menarche. There is no current consensus on the investigations for prepubertal girls with isolated vaginal bleeding with no other signs of precocious puberty.Objective: The objective of our study is to evaluate the factors associated with persistent isolated cyclical vaginal bleeding including clinical pres...

ea0027p39 | (1) | BSPED2011

Treatment strategies and outcomes of paediatric Craniopharyngioma since 2005: a single centre experience

Upadrasta Swathi , Doss Arun , Mallucci Conor , Pizer Barry , Abernethy Laurence , Das Urmi , Dharmiaj Poonam , Didi Mohamed , Blair Jo

Background: The Craniopharyngioma service in our centre has changed since 2005 with a standardised preoperative assessment and a new approach to surgery and use of radiotherapy. We review the subsequent outcomes.Treatment strategy: Preoperative endocrinology: prior to dexamethasone therapy: standard dose short synacthen test (SST), thyroid function test (TFT), IGF1, LH, FSH, testosterone/oestradiol±GH stimulation test. Staging: MRI and tumour stagin...