Searchable abstracts of presentations at key conferences in endocrinology

ea0020p651 | Reproduction | ECE2009

Screening of maternal thyreopathies in Slovakia: is it worth it?

Urbankova Helena , Hruska Jan , Vanuga Peter

Background: Newborn screening is the only systematic work-up of thyroid disorders in Slovakia with unambigously proven positivities. There is wide discussion regarding the screening of thyreopathies in specific risk groups such as pregnant women.Aims: To study the gynaecologist and endocrinologist co-operation in screening pregnant patients from region of Liptov and Orava for autoimmune thyroiditis.Subjects and methods: The partici...

ea0041ep80 | Adrenal cortex (to include Cushing's) | ECE2016

Cushing syndrome with ectopic secretion of ACTH by a lung carcinoma

Moravcikova Elena , Kulich Michal , Urbankova Helena , Gregova Juliana , Vanuga Peter

Introduction: A form of ACTH-dependent Cushing syndrome is an ectopic production of ACTH. The aetiology can by benign lesion or a malignant non-pituitary tumor, which is more common. The prevalence of endogenous Cushing syndrome is 1 in 26 000. Ectopic ACTH secretion is responsible for 7–15% of the cases. Principal position of the ACTH-producing tumor is in lungs – a bronchial endocrine tumor and small cell lung cancer. Small peripheral bronchial carcinoids can easil...

ea0037ep731 | Pituitary: clinical | ECE2015

Carney complex – a case report

Urbankova Helena , Kulich Michal , Veteskova Elena , Vanuga Peter

Carney complex (CNC) is rare autosomal dominant disorder, which was firstly described as a combination of manifestation of myxomas, spotty skin pigmentation and endocrine overactivity in 1985. This condition affects many organs and varies in clinical manifestation. The presence of at least two clinical signs is considered as pathognomonic with regard to a sporadic form of CNC, and an evidence of at least one sign with simultaneous manifestation of CNC in any of first degree re...

ea0099ep931 | Reproductive and Developmental Endocrinology | ECE2024

Two sides of the same coin: infertile couple

Moravcikova Elena , Urbankova Helena , Vanuga Peter , Kulich Michal

Introduction: Our case is a young couple, both endocrinologically monitored from childhood. Woman with diagnosis of oligomenorrhea – secondary amenorrhea. Man with delayed puberty. After complex endocrinological screening both diagnoses was changed to: woman diagnosed with prolactinoma and man with isolated idiopathic central hypogonadism (IICH). They were trying to concieve for 10 years with no succes.Case: Woman: At 17 years of age diagno...

ea0090ep692 | Pituitary and Neuroendocrinology | ECE2023

Macrohormones (“incidental hormones”) – a diagnostic challenge in endocrinology: macro-ACTH

Vanuga Peter , Urbankova Helena , Sagova Ivana , Kulich Michal , Huba Peter , Vanuga Anton

Background: If the laboratory results are not compatible with the patient’s clinical symptoms, the presence of possible test interference should be considered. Despite the excellent quality of immunoassays, it is currently estimated that they may be susceptible to several types of interference that may lead to patient misdiagnosis.Case report: In our case report we present a 71-year-old woman with confirmation of macro-adrenocorticotropic hormone (m...

ea0035p260 | Clinical case reports Pituitary/Adrenal | ECE2014

Hyporeninemic hypoaldosteronism with severe hyperkalemia following adrenalectomy for primary hyperaldosteronism : a case report

Pura Mikulas , Malina Jan , Machalekova Katarina , Imreova Helena , Kentos Peter , Urbankova Helena , Vanuga Peter

Background: Post-adrenalectomy persistent hyperkalemia, that lasts >3 months and needs to be treated, is a potentially serious, but not apprehensively investigated complication after surgical treatment in patients with aldosterone-producing adenomas (APA).Case report: A 53-year-old male presented type 2 diabetes mellitus and a 10-year history of resistant hypertension requiring multidrug treatment with antihypertensives of eight different classes. Pr...

ea0056ep106 | Pituitary and Neuroendocrinology | ECE2018

Rare combination of Acromegaly and Klinefelter syndrome

Sagova Ivana , Pavai Dusan , Stancik Matej , Kantarova Daniela , Urbankova Helena , Gregova Juliana , Vanuga Anton , Vanuga Peter

Acromegaly is a rare disorder usually caused by a benign tumour of the pituitary gland. Long-term presence of elevated growth hormone (GH) and insulin like growth factor I (IGF-I) levels accompanying this disease is associated with complications such as heart failure, cerebrovascular disease, diabetes mellitus, sleep apnoea and arthropathy. Incidence of acromegaly is 3-5 patients per million per year. Klinefelter syndrome is ...

ea0049ep1086 | Clinical case reports - Pituitary/Adrenal | ECE2017

Combination of turner syndrome and congenital adrenal hyperplasia: a rare case report

Sagova Ivana , Pavai Dušan , Stančik Matej , Urbankova Helena , Gregova Juliana , Vaňuga Anton , Vaňuga Peter

Combination of Turner syndrome (TS) and classical congenital adrenal hyperplasia (CAH) is rare worldwide. Incidence of CAH - autosomal recessive disorders characterized by enzyme defect of steroidogenic pathway, of which 90% ocuurs in the CYP21A2 gene coding 21-hydroxylase is 1:10000-16000. Incidencie of Turner syndrome is 1:2500 worldwide. Phenotypically, females with TS may present with a wide spectrum of clinical features. They may exhibit short stature, virilization, prema...