Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep107 | Adrenal and Cardiovascular Endocrinology | ECE2020

A congenital adrenal hyperplasia patientpresented with myocardial infarction due to inadequate glucocorticoid therapy

Melin Uygur Meliha , Dogan Ali

Congenital adrenal hyperplasia (CAH) refers to an autosomal recessive condition due to 21 hydroxylase (21OHD) deficiency, is characterized by impaired biosynthesis of glucocorticoid and mineralocorticoid. The consequent increase in the ACTH leads to bilateral adrenocortical hyperplasia and hyperandrogenism. Nonclassic CAH (NCCAH) manifests with a less severe clinic that presents later in life with the sympthoms of excessive androgen production. Clinical features include premat...

ea0081p145 | Pituitary and Neuroendocrinology | ECE2022

The role of advanced glycation end products on vertebral fractures in patients with acromegaly

Melin Uygur Meliha , Dereli Yazıcı Dilek , Gogas Yavuz Dilek

Introduction: Acromegalic osteopathy is an emerging complication characterized by high risk for vertebral fractures (VFS), whereas bone mineral density (BMD) may not be useful to predict the risk. Recent studies have reported that increased advenced glycation end products (AGEs) are associated with bone fragility. We aimed to evaluate the relationship between AGEs and VFs in patients with acromegaly.Study design: Cross-sectionalPat...

ea0049ep47 | Adrenal cortex (to include Cushing's) | ECE2017

Effect of adrenal mass lateralization on diagnostic tests in patients with Cushing

Tarcin Ozlem Ustay , Pehlevan Emre , Imre Eren , Uygur Melin , Deyneli Oguzhan , Yavuz Dilek Gogas

The frequency of adrenal masses is increasing in parallel with the progress of the technology. Most of these masses, which are detected by chance, are not functional, and only a part of them are exposed to an excess of hormone. The most common dysfunction in masses with hormonal activity is hypercortisolism. However, the diagnosis of Cushing’s disease is based on more than one test. In this study, we intended to compare the values of screening tests to determine whether t...

ea0041ep144 | Calcium and Vitamin D metabolism | ECE2016

Bone mineral density is associated with hypercalciuria in primary hyperparathyroidism

Yavuz Dilek Gogas , Tekin Bahar , Buket Bayram F. , Melin Uygur M.

Aim: The most common clinical presentation of primary hyperparathyroidism (PHPT) is asymptomatıc and it is diagnosed incidentally without developing complications.In our study, we aimed to examine the characteristics of participants with primary hyperparathyroidism and the relationship between bone mineral density (BMD) and hypercalciuria.Methods: Consecutive 191 normocalciuric (24-h urinary calcium<400 mg/day) patients with PHPT (51±13 yea...

ea0041ep145 | Calcium and Vitamin D metabolism | ECE2016

Bone mineral density measurement in newly diagnosed primary hyperparathyroidism patients

Tekin Bahar , Melin Uygur M. , Buket Bayram F. , Yavuz Dilek Gogas

Aim: Clinical presentation of primary hyperparathyroidism (PHPT) differs between populations. In this study, we aimed to examine bone mineral density (BMD) and bone metabolism parameters in newly diagnosed and untreated PHPT patients in a single endocrine center in İstanbul, Turkey.Methods: Consecutive 256 PHPT patients (50.7±14 years, F/M:205/51) and 89 healthy controls (38.8±10 years, F/M:67/22) were included in the study. Serum calcium...

ea0035p1048 | Thyroid (non-cancer) | ECE2014

Adherence of levothyroxine treatment in primary hypothyroid patients in Turkey: a multicenter study

Yavuz Dilek Gogas , Keskin Lezzan , Atmaca Aysegul , Dikbas Oguz , Hekimsoy Zeliha , Sahin Ibrahim , Yalin Serap , Yilmaz Murat , Uygur Melin , Yazici Dilek , Sarac Fulden , Sancak Seda , Sekizkardes Sibel , Asmaz Ozlem

Non adherence to medication schedules by patients with chronic illnesses has long been recognized as a problem. The aim of this study is to evaluate levothyroxine (L-T4) compliance, daily dosage and TSH levels under treatment in primary hypothyroid patients.We included 1636 primary hypothyroid patients over 1 year under L-T4 (F/M: 1469/167, 46±13 years of age) included from 11 tertiary health care ...