Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep129 | Steroids, development and paediatric endocrinology | ECE2015

Effect of metformin on sex steroid levels in postmenopausal type 2 diabetic patients

Unluturk Ugur , Bakar Filiz , Urun Yuksel , Nebioglu Serpil , Uysal Ali Riza

Introduction: Metformin treatment was associated with decreased risk of various cancers including breast cancer. Exposure to sex steroid is related with increased risk of breast cancer. In this study, we aimed to evaluate the effect of metformin treatment on serum levels of sex steroids and sex hormone binding globulin (SHBG) in postmenopausal women with type 2 diabetes mellitus.Methods: Postmenopausal patients with newly diagnosed type 2 diabetes were r...

ea0035p527 | Endocrine tumours and neoplasia | ECE2014

Could non-functional adrenal incidentaloma be a risk factor for atherosclerosis and metabolic disturbances?

Emral Rifat , Kose Ayla Demir , Corapcioglu Demet , Demir Ozgur , Uysal Ali Riza

Introduction: Non-functional adrenal incidentalomas (AI) are currently quite important since they can also cause metabolic disturbances. This study was designed to evaluate possible insulin resistance indicators and cardiovascular risk factors in patients with non-functional AI.Patients and methods: 83 patients with non-functional AI were enrolled to the study. Control group consisted of 56 patients without any adrenal lesion. Fasting blood glucose, and ...

ea0032p130 | Calcium and Vitamin D metabolism | ECE2013

Fahr’s disease with dystonia: a case report

Aydogan Berna Imge , Unluturk Ugur , Can Ferda , Sahin Mustafa , Uysal Ali Riza

Background: Fahr’s disease is a rare degenerative disorder characterized by symmetrical and bilateral intracranial calcification. Movement disorders are the most common symptoms of Fahr’s disease and dystonia is an uncommon presentation which accounts for only 8% of symptomatic patients.Case report: A 47 years old female admitted to emergency department with involuntary movements of extremities and anxiety. Neurological examination was normal e...

ea0037oc3.4 | Calcium, vitamin D and bone | ECE2015

Cardiovascular risk factors in patients with medically observed and operated primary hyperparathyroidism

Colak Sevgi , Aydogan Berna Imge , Canpolat Asena Gokcay , Kaya Cansin Tulunay , Sahin Mustafa , Corapcioglu Demet , Uysal Ali Riza , Emral Rifat

Introduction: It is known that patients with primary hyperparathyroidism (PHPT) have an increased cardiovascular morbidity and mortality. In our study, we aimed to investigate the cardiovascular risk factors in medically observed and operated PHPT patients.Materials and methods: Twenty-nine medically observed (group A), 25 pre-operative (group B) and 23 post-operative (group C) patients with PHPT and 26 normocalcemic patients as control group (group D) w...

ea0037ep278 | Calcium and Vitamin D metabolism | ECE2015

25-OH vitamin D: a predictor of clinical outcomes in primary hyperparathyroidism

Sahin Mustafa , Aycicek Gozde Sengul , Corapcioglu Demet , Emral Rifat , Gullu Sevim , Erdogan Murat Faik , Gedik Vedia Tonyukuk , Baskal Nilgun , Uysal Ali Riza

Objectives: We aimed to find if there is any relationship between vitamin D levels and clinical, laboratory parameters and osteoporosis, in primary hyperparathyroidism (PHPT).Material and methods: 128 patients with PHPT and 30 patients as a control group were analysed. Patients with PHPT were grouped due to vitamin D levels and levels low than 20 μg/ml accepted as deficiency.Results: Patients with 25-OH vitamin D <20 &#956...

ea0037ep823 | Pituitary: clinical | ECE2015

Clinical features and treatment outcomes of resistant acromegaly patients: a single-centre study

Demir Ozgur , Canpolat Asena Gokcay , Aydogan Berna Imge , Keskin Caglar , Canlar Sule , Sahin Mustafa , Emral Rifat , Gullu Sevim , Gedik Vedia Tonyukuk , Uysal Ali Riza , Corapcioglu Demet

Introduction: Disease control in acromegaly can be achieved by surgery, medical treatment, and radiotherapy either alone or in combination. The acromegaly patients whom tumour shrinkage cannot be provided or growth hormone levels do not decrease under multiple treatment modalities are designated as resistant acromegaly. We aimed in our study to evaluate the clinical features of resistant acromegaly patients and determine their responds to different treatment modalities.<p ...

ea0037ep900 | Thyroid cancer | ECE2015

Concomitant thyroid nodules in primary hyperparathyroidism

Sahin Mustafa , aycicek Gozde Sengul , corapcioglu Demet , emral Rifat , gullu Sevim , erdogan Murat Faik , Gedik Vedia Tonyukuk , Baskal Nilgun , Uysal Ali Riza

Objectives: Coexisting thyroid nodules affect the treatment choice for PHPT. We aimed to evaluate the incidence of concomitant thyroid nodules in patients with primary hyperparathyroidism and to investigate the relationship between thyroid nodule volume, thyroid gland volume and thyroid nodules with clinical and laboratory parameters.Materials and methods: This study was carried out at Ankara University Endocrinology and Metabolism Department. 183 patien...

ea0032p1103 | Thyroid cancer | ECE2013

Evaluation of whole-body scan, stimulated thyroglobulin after thyroxine withdrawal vs recombinant TSH administration according to the risk groups of tumor recurrence

Sahin Mustafa , Aydogan Berna Imge , Yuksel Bagdagul , Erdogan Murat Faik , Gullu Sevim , Emral Rifat , Corapcioglu Demet , Baskal Nilgun , Uysal Ali Riza

Background: Recombinant human thyroid-stimulating hormone (rhTSH)-stimulated serum thyroglobulin (Tg) (s-Tg) and (131)I whole-body scanning (WBS) are supposed to provide equal diagnostic information with thyroxine withdrawal (THW) at follow-up thyroid cancer patients without the symptoms of hypothyroidism. We aimed to compare the WBS and s-Tg levels after thyrogen injection and thyroid hormone withdrawal for tumor recurrence/persistance according to the risk groups.<p clas...

ea0020p604 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Results of acromegaly patients treated with surgery and/or somatostatin analog and/or radiotherapy in a University Hospital in Turkey

Demir Ozgur , Tonyukuk Gedik Vedia , Emral Rifat , Faik Erdogan Murat , Gullu Sevim , Corapcioglu Demet , Uysal Ali Riza , Baskal Nilgun , Kamel Nuri

Background: Transsphenoidal adenomectomy is the first choice of therapy, but about 50% of patients are not cured and require medical treatment and/or radiotherapy. We retrospectively analyzed the data on surgery, sandostatin analog therapy, radiotherapy and the combination of them.Materials-methods: The records of the 96 female and 70 male, totally 166 acromegalic patients who had been followed in Ankara University, Endocrinology and Metabolic Diseases D...