Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1233 | Obesity | ICEECE2012

Anthropometric, hormonal and nutritional correlates of epicardial fat in obese women

Vicennati V. , Cavazza C. , Garelli S. , Pizzi C. , Bugiardini R. , Rinaldi E. , Pagotto U. , Pasquali R.

Background and aim: Epicardial fat (EF) is a metabolically active organ as well as visceral fat (VF). EF has been recognized as a potential additional marker of cardiac risk in obesity and type 2 diabetes. This study wants to assess the relation between EF and VF and the correlation with nutritional and hormonal parameters.Material and Methods: Fifty-nine overweight/obese women were enrolled in the study. All women underwent anthropometric measurements, ...

ea0029oc7.6 | Adrenal Clinical | ICEECE2012

Progressively increased patterns of subclinical cortisol hypersecretion in adrenal incidentalomas differently predict major metabolic and cardiovascular outcomes: a large cross-sectional study

Di Dalmazi G. , Vicennati V. , Rinaldi E. , Morselli-Labate A. , Giampalma E. , Mosconi C. , Pagotto U. , Pasquali R.

Background: Subclinical Cushing’s syndrome (SCS) is defined as alterations in hypothalamic–pituitary–adrenal axis without classic signs or symptoms of glucocorticoid excess. It is still controversial whether SCS leads to metabolic and cardiovascular diseases, and if the degree of subclinical hypercortisolism may predict these clinical outcomes.Aim: To evaluate the prevalence of hypertension, type-2 diabetes (T2D), coronary heart disease (C...

ea0029oc12.1 | Obesity Clinical | ICEECE2012

Circulating endocannabinoids are associated to cardiometabolic alterations independently from adiposity

Fanelli F. , Mezzullo M. , Belluomo I. , Di Lallo V. , Colavita M. , Baccini M. , Casadio E. , Ibarra Gasparini D. , Vicennati V. , Pasquali R. , Pagotto U.

Obesity is characterized by an increase of endocannabinoid circulating levels as anandamide (AEA) and 2-arachidonoyl-glycerol (2AG). Whether these lipids represent a biomarker of dysmetabolism or merely reflect the fat mass spill-over is still unclear. After generating rigorous, gender specific, plasma reference intervals by 2D-liquid chromatography-tandem mass spectrometry, we defined the 97.5thcentile of endocannabinoid distribution in the normal population as the cut-off ab...

ea0026p330 | Obesity | ECE2011

Haematic circulating endocannabinoids (ECs) in lean, overweight and obese: the role of the gender

Fanelli F , Di Lallo V D , Belluomo I , Casadio E , Baccini M , Ibarra Gasparini D , Vicennati V , Pasquali R , Pagotto Uberto

A number of publications recently provided measurements of plasma ECs by liquid chromatography–tandem mass spectrometry (LC–MS/MS), however the reported circulating levels in normal subjects are scattered in a very wide range of concentrations. A quantitative LC–MS/MS method for anandamide (AEA), palmitoylethanolamide (PEA), oleoylethanolamyde (OEA) and 2arachidonoyl-glycerol (2AG), chromatographically resolved by its inactive isomer 1AG, was validated in house....