Searchable abstracts of presentations at key conferences in endocrinology

ea0081p598 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Impact of Bariatric Surgery on the liver - An adolescent cohort

von Hafe Madalena , Chaves Joana , Neves Joao Sergio , Borges-Canha Marta , Vale Catarina , Lourenco Ines , Corujeira Susana , Campos Miguel

Introduction: Obese patients are at an increased risk of develop nonalcoholic fatty liver disease. Evidence supports that bariatric surgery might have an important impact on hepatic profile in obese adults. Literature suggests that bariatric surgery in adolescents might decrease the prevalence of some comorbidities, but information about its impact on liver profile and steatosis and fibrosis risk remains scarce.Aim: To evaluate the impact of bariatric su...

ea0081p599 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Effect of bariatric surgery on metabolic profile − a pediatric cohort

von Hafe Madalena , Chaves Joana , Sergio Neves Joao , Borges-Canha Marta , Vale Catarina , Corujeira Susana , Campos Miguel

Introduction: Obesity is a complex multifactorial disease and its prevalence in pediatric age has increased. Obesity prejudices the individual metabolic profile due to the adipotoxicity involved in this condition. Bariatric surgery improves the weight of obese patients along with metabolic comorbidities, being today one of the most effective treatments for obesity. Time of exposure to adipotoxicity appears to be an important risk factor for the development of metabolic complic...

ea0049gp217 | Thyroid 3 | ECE2017

Thyroid function in heart failure with preserved ejection fraction (HFpEF) – evaluation of serum and myocardial thyroid hormones in an animal model of HFpEF

Sergio Neves Joao , Vale Catarina , Almeida-Coelho Joao , Barez-Lopez Soledad , Jesus Obregon Maria , Isabel Oliveira Ana , Lourenco Andre , Falcao-Pires Ines , Carvalho Davide , Leite-Moreira Adelino

Introduction: Thyroid hormones play a central role in the regulation of the cardiovascular system. Heart failure with preserved ejection fraction (HFpEF) is responsible for more than 50% of all heart failure cases and its main pathophysiological alteration is diastolic dysfunction. Diminished thyroid function is known to predominantly impair diastolic function, however the thyroid hormone status in HFpEF remains largely unknown.Methods: We evaluated an a...

ea0081rc11.6 | Rapid Communications 11: Thyroid 2 | ECE2022

Association of thyroid hormones with clinical status and cardiovascular outcomes of HFpEF patients

Leite Ana Rita , Neves Joao Sergio , Vasques-Novoa Francisco , Saraiva Francisca A , Cristina Oliveira Ana , Borges-Canha Marta , von Hafe Madalena , Vale Catarina , Angelico-Goncalves Antonio , Leite-Moreira Adelino F

Introduction: Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome with high mortality, for which there are few disease modifying therapeutics. Thyroid axis dysfunction is common in heart failure (HF) and may contribute to the pathogenesis of HFpEF. However, the association of thyroid hormones (TH) with the clinical status of HFpEF patients and their prognostic impact in this syndrome are not clear. Methods: We evaluated 93 parti...

ea0090p563 | Adrenal and Cardiovascular Endocrinology | ECE2023

Influence of liver steatosis and fibrosis on cardiovascular function and prognosis of HFpEF patients

Rita Leite Ana , Borges-Canha Marta , Angelico-Goncalves Antonio , Vasques-Novoa Francisco , Saraiva Francisca , Cristina Oliveira Ana , von Hafe Madalena , Vale Catarina , Carvalho Davide , Sergio Neves Joao , Leite-Moreira Adelino F.

Introduction: Non-alcoholic fatty liver disease (NAFLD) and Heart Failure with Preserved Ejection Fraction (HFpEF) are two syndromes with increasing clinical relevance, mainly due to the rising prevalence of metabolic syndrome. Despite sharing a common metabolic background, the association between NAFLD severity and HFpEF has not yet been well explored.Aim: To evaluate the association of NAFLD steatosis and fibrosis scores with cardiovascular function an...

ea0073aep212 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

Influence of diabetes in heart failure with preserved ejection fraction

Borges-Canha Marta , Francisco Vasques-Nóvoa , Saraiva Francisca , Leite Ana Rita , Oliveira Ana Cristina , Neves Joao Sergio , Hafe Madalena von , Vale Catarina , Carvalho Davide , Adelino F. Leite-Moreira

IntroductionHeart Failure with Preserved Ejection Fraction (HFpEF) denotes a growing challenge due to the population aging and the rising prevalence of cardiovascular risk factors.AimWe aimed to evaluate the influence of the diagnosis of diabetes mellitus (DM) on the signs and symptoms, comorbidities and echocardiographic and vascular evaluation of patients with HFpEF in a stable phase....

ea0090ep286 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Prediabetes remission after bariatric surgery: A 4-years follow-up study

Borges-Canha Marta , Neves Joao Sergio , Silva Maria , Mendonca Fernando , Moreno Telma , Ribeiro Sara , Vale Catarina , Goncalves Juliana , Ferreira Helena Urbano , Santos Sara , Calheiros Raquel , Meira Ines , Menino Joao , Guerreiro Vanessa , Pedro Jorge , Varela Ana , Souto Selma , Lima da Costa Eduardo , Freitas Paula , Carvalho Davide , Group CRIO

Background: Bariatric surgery leads to weight loss and to cardiometabolic risk improvement. Although prediabetes remission after bariatric surgery is biologically plausible, data on this topic is scarce.Aim: We aimed to access pre-diabetes remission rate and clinical predictors of remission in a 4 year follow up period.Methods: Observational longitudinal study including patients with morbid obesity and prediabetes submitted to bari...