Searchable abstracts of presentations at key conferences in endocrinology

ea0063ep25 | Calcium and Bone | ECE2019

Treatment sequence after teriparatide

Valea Ana , Carsote Mara , Gheorghisan-Galateanu Ancuta Augustina

Introduction: Teriparatide is prescribed for severe osteoporosis based on national protocols. The osteoanabolic drug is followed by an anti-resorbtive medication.Aim: We analyze the treatment sequence options after Teriparatide in patients who finished the 2-year protocol or were early droppers.Material and method: This is a real life study based on Romanian protocol of Teriparatide for severe primary or/and glucocorticoid osteopor...

ea0049ep979 | Pituitary - Clinical | ECE2017

Giant macroprolactinoma in women still exist

Dragomir Laura , Florian Stefan , Valea Ana , Ghervan Cristina

Background: Prolactinomas are the most common hormone-secreting pituitary tumors and are a common cause of anovulation and infertility. Giant prolactinomas (0.5–4.4% of all pituitary tumors) are rare tumors characterized by their large size (>4 cm), compressive symptoms and extremely high prolactin secretion (>1000 ng/ml). Men are most commonly affected, with a reported male to female ratio of 9:1.Case report: We present the rare case of 53-...

ea0063p420 | Adrenal and Neuroendocrine Tumours 2 | ECE2019

Premature ovarian failure in a patient with schmidt syndrome

Valea Ana , Moldovan Cristina , Hritiuc Andreea , Agachi Irina , Carsote Mara , Emanuela Georgescu Carmen

Introduction: Premature ovarian failure (POF) may be a part of autoimmune polyglandular syndromes that involves multiple endocrine and systemic conditions due to autoimmunity.Material and methods: We aim to present the case of a young women diagnosed with POF and Schmidt syndrome. The patient was followed in different tertiary centers of endocrinology. The informed consent was obtained.Case report: A 31-year old patient with no pri...

ea0049ep117 | Clinical case reports - Pituitary/Adrenal | ECE2017

Endocrine masses displayed as incidentalomas in patients with unilateral nephrectomy

Ghemigian Adina , Petrova Eugenia , Dumitru Nicoleta , Buruiana Andra , Carsote Mara , Valea Ana

Introduction: Menopausal adrenal tumours may be elements of a complex panel of co-morbidities. Some of these are represented by the presence of a second pathology requiring surgery at the kidney level.Aim: We aim to introduce a series of two cases involving menopausal women who were referred for specific endocrine assays after they had a unilateral nephrectomy (UN).Method: This is a cases series observational study. The patients ga...

ea0049ep846 | Clinical case reports - Pituitary/Adrenal | ECE2017

Breast cancer and newly discovered non-secretor pituitary mass- as risk of metastases?

Valea Ana , Oprisor Iulia , Carsote Mara , Pop Dan Dumitru , Morar Andra , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Even if breast cancer is rare cause of pituitary metastases, the diagnosis of a pituitary adenoma, shortly after surgery for breast cancer, raises suspicion of a possible secondary determinations.Material and method: This is a case report revealing the medical history and endocrine profile of a female with breast cancer and pituitary macroadenoma.Case data: A 64-year old non-smoking female (with menopause at age of 52...

ea0041ep49 | Adrenal cortex (to include Cushing's) | ECE2016

Cushing’ s disease, hasimoto’s thyroiditis and severe hyperandrogenemia

Valea Ana , Ciocan Irina , Carsote Mara , Morar Andra , Pop Dan Dumitru , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Cushing’s disease (CD) is caused by high adrenocorticotropic hormone (ACTH), usually by a pituitary microadenoma.Material and method: This is a case report investigated in several Romanian centers by performing: morning plasma cortisol, circadian rhythm of plasma cortisol, plasma ACTH, dexamethasone (DXM) suppression tests.Case data: A 57-year female, known with hypertension and osteopenia, was ...

ea0041ep51 | Adrenal cortex (to include Cushing's) | ECE2016

Pediatric Cushing’s disease and paraduodenal tumor

Valea Ana , Breaban Maria , Carsote Mara , Morar Andra , Dumitru Pop Dan , Emanuela Georgescu Carmen , Ghervan Cristina

Introduction: Cushing’s disease (CD) in youth represents a challenge especially related to the therapy and long-term management.Materials and methods: We report the medical history of a child with CD who was followed-up for 7 years. Suggestive endocrine panel and imagery is exposed.Case presentation: A 19-year female was diagnosed at age of 12 with CD. Clinical assessment revealed: weight gain, headache, hyperpigmentation pred...

ea0041ep70 | Adrenal cortex (to include Cushing's) | ECE2016

Large aortic aneurism and left coronary artery calcifications: incidental findings at adrenal incidentaloma assessment

Carsote Mara , Dobrescu Mariana , Dumitrascu Anda , Gruia Adriana , Valea Ana , Ghemigian Adina

Introduction: In cases with high-risk metabolic profile the investigations may lead to the discovery of an adrenal tumor (AT). Complex endocrine investigations including computed tomography (CT) scans may point anomalies of the vessels as coronary artery or abdominal aorta.Aim: We report a case associating an AT and severe cardiovascular anomalies which are discovered during endocrine investigations.Case data: A 72-year prior smoke...

ea0041ep71 | Adrenal cortex (to include Cushing's) | ECE2016

From mild abdominal pain to large right adrenal cyst

Moraru Dana , Chirita Corina , Tataru Simona , Trandafir Ioana , Carsote Mara , Valea Ana , Petrescu Razvan

Introduction: Cystic lesions of the adrenals are rare and they may develop asymptomatically for a long period of time. Females seem to be more affected and lesion is typically unilateral.Aim: We report a case of young female case incidentally found with a large adrenal pure cystic mass.Case data: A 24-year non-smoking female patient with regular menses since the age of 14 complained of mild abdominal pain for a few days without cor...

ea0041ep81 | Adrenal cortex (to include Cushing's) | ECE2016

Asynchronous bilateral adrenal masses: from surgery to endocrine follow-up

Valea Ana , Ciocan Irina , Pop Dan Dumitru , Carsote Mara , Muntean Iulia , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Cushing’s syndrome (CS) is correlated with prolonged exposure to high levels of glucocorticoid hormones. Although the most common cause is exogenous adrenal tumors incidentally discovered (incidentaloma) may underline CS.Material and method: This is a case presentation of an adult patient. Specific tests for CS have been used: morning plasma cortisol and circadian rhythm, plasma ACTH, testosterone, dexamethasone (DXM) suppression test....