Searchable abstracts of presentations at key conferences in endocrinology

ea0022p636 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Evaluation of quality of life in patients with acromegaly using the acromegaly quality of life questionnaire (AcroQoL)

Vandeva Silvia , Nachev Emil , Nikolov Mario , Matrozova Joanna , Kalinov Krasimir , Zacharieva Sabina

Introduction: Acromegaly is a chronic disease with a serious impact on patients’ morbidity, mortality and health-related quality of life (HRQOL). Recently a disease-specific questionnaire assessing HRQOL in acromegaly was developed (AcroQoL). Using this tool we have compared QoL in patients with controlled versus uncontrolled acromegaly.Patients and methods: It was a prospective, cross-sectional study. For the period 2007–December 2008 163 pati...

ea0026p655 | Clinical case reports | ECE2011

Impact of two novel mutations of calcium sensing receptor (CaSR) gene on calcium metabolism: two clinical case reports

Livadariu Elena , Auriemma Renata Simona , Rydlewski Catherine , Vandeva Silvia , Thonnard Anne Sophie , Betea Daniela , Daly Adrian F , Beckers Albert

Disorders of calcium metabolism arise in a familial or sporadic setting. The resulting hypo- or hypercalcemia can induce serious clinical features. Calcium sensing receptor (CaSR) plays a key role in maintaining this balance and its molecular investigation is useful to determine the nature of a certain condition or to choose the appropriate therapeutic approach.In the present study we reported two clinical cases. A 16-year-old patient had a mild hypercal...