Searchable abstracts of presentations at key conferences in endocrinology

ea0081p741 | Thyroid | ECE2022

Efficacy of radioactive iodine treatment in Graves Disease using a calculated 131I dose and predictive factors of success in a Portuguese cohort

Franco Sara , Teixeira Ferreira Rita , Cardoso Ferreira Ines , Quitalo Ana , Barbosa David , Manuel Costa Maria , Vara Luiz Henrique , Raimundo Luisa , Isabel Santos Ana

Aim: Dose corrected for thyroid gland size is one of the methods used to determine radioactive iodine (RAI) activity for patients with Graves disease (GD). This study was aimed to investigate the real-world success rate of this method and the predictors of success after first treatment.Methods: This is a retrospective study of 80 patients with GD treated between 2014 and 2020 in a tertiary referral hospital in Almada, Portugal. The successful group was d...

ea0090p388 | Endocrine-related Cancer | ECE2023

PRRT 177Lu-DOTA-TATE in pancreatic neuroendocrine tumors – When to initiate?

Franco Sara , Lucena Sampaio Ines , Ferreira Goncalo , Barbosa Daniel , Gil-Santos Sara , Vara Luiz Henrique , Paula Santos Ana , Torres Isabel , Duarte Hugo

Introduction: The best timing for PRRT (peptide receptor radionuclide therapy) in the case of pancreatic neuroendocrine tumors (panNETs) is still to define, as randomized prospective trials are lacking. Recent studies suggest that some systemic therapies can affect response to PRRT, favoring an earlier use of the latter.Objective: To determine the efficacy and toxicity of PRRT, comparing its results when used as a second line systemic therapy (a...

ea0070aep721 | Pituitary and Neuroendocrinology | ECE2020

Septo-optic dysplasia with late-onset diagnosis: An uncommon presentation of a rare disease

Duarte Vitória , Ivo Catarina , Veríssimo David , Franco Sara , Bastos Filipa , Marcelino Mafalda , Vara Luiz Henrique , Portugal Jorge

Background: Septo-optic dysplasia (SOD), also known as de-Morsier syndrome, is a rare congenital disorder characterized by any combination of optic nerve hypoplasia, pituitary dysfunction and midline abnormalities of the brain. Clinical diagnosis requires the presence of at least two of the features. This disorder is equally prevalent in males and females, with a reported incidence of 1/10,000 live births. There is wide variation in the severity of the clinical features found....

ea0070ep269 | Endocrine-related Cancer | ECE2020

Multiple endocrine neoplasia: A case series of 7 families

Duarte Vitória , Ivo Catarina , Veríssimo David , Marcelino Mafalda , Vara Luiz Henrique , Franco Sara , Bastos Filipa , Manita Isabel , Raimundo Luisa , Portugal Jorge

Introduction: Multiple endocrine neoplasia (MEN) is a rare genetic syndrome characterized by occurrence of tumors involving two or more endocrine glands. Four types are described: MEN1, MEN2, MEN3 and the recently identi&#-1279;ed MEN4. Due to the complexity of the syndromes, it is difficult to manage these patients. Our objective was to describe the clinical features of individuals from 7 families with a diagnosis of MEN1 or MEN2 and identify current challenges in clinical pr...

ea0073ep210 | Thyroid | ECE2021

Epithelioid hemangioendothelioma with thyroid involvement – case report

Franco Sara , Cardoso Catarina , Correia Rafaela , Sequeira Mafalda , Dinis Sousa Magno , Filipa C. Bastos , Sequeira Pedro , Raquel Miranda Ana , Abecassis Francisca , Ana Gonçalves Ferreira , Barbosa David , Vara Luiz Henrique , Jorge da Cunha Oliveira

Epithelioid hemangioendotheliomas (EHE) are rare vascular tumors that are typically low to intermediate grade, but they can also have an aggressive behaviour. Mortality rate is dependent on the tumor location. It is frequently a solitary lesion located in the superficial or deep soft tissues, but they can be found in liver, lungs (normally multifocal), pleura, bones, lymph nodes and rarely in the thyroid gland. We describe a case of metastatic EHE with involvement of the thyro...