Searchable abstracts of presentations at key conferences in endocrinology

ea0032p78 | Bone and Osteoporosis | ECE2013

Effects of Denosumab treatment on insulin resistance in postmenopausal women with osteoporosis

Tzioras Konstantinos , Mizamtsidi Maria , Chronaiou Aikaterini , Vasiliou Georgia , Tagara Sofia , Vryonidou Andromachi

Introduction: Denosumab is a new pharmacotherapy option for postmenopausal osteoporosis. It is a human monoclonal antibody against RANKL, acting as an osteoprotegerin (OPG) analog. Recently, osteoprotegerin levels were found to be elevated in type two diabetes while insulin resistance was shown to be positively associated with decreased serum OPG levels, in healthy obese subjects. However, no study has been conducted in order to clarify the effect of anti-RANKL factors adminis...

ea0022p537 | Male reproduction | ECE2010

A case of partial androgen insensitivity syndrome with absence of breast development

Vryonidou Andromachi , Klonaris Nikos , Badila Alexandros , Vasiliou Georgia , Tagara Sofia , Poulias Heraklis

Introduction: Partial androgen insensitivity syndrome (PAIS) is a heterogeneous group of intersex disorders arising from tissue resistance to androgen action due to mutations of the androgen receptor. The phenotypic expression of the syndrome varies considerably and external genitalia’s masculinization depends on residual activity of the androgen receptor while gynecomastia is observed in most of the cases.Case report: We present the case of a 16 ye...

ea0020p364 | Diabetes and Cardiovascular | ECE2009

Pancreatic function in β-thalassemic patients

Vryonidou-Bompota Andromachi , Loi Vasiliki , Vasiliou Georgia , Terzi Thomais , Karagianni Olympia , Tzioras Costas , Phenekos Costas

Background & aims: Impaired glucose tolerance and diabetes as well as cardiac dysfunction are known complications in homozygous beta-thalassemic transfused patients due to iron overload. We aimed to study pancreatic alpha and beta-cell function in regularly transfused patients with homozygous beta-thalassemia and to investigate if cardiac dysfunction may correlate with the development of impaired glucose metabolism.Methods: An oral glucose tolerance ...