Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp23 | Calcium and Bone 1 | ECE2019

Study of hsa-miR-30e miRNA as a biomarker in identifying multiple gland disease in sporadic primary hyperparathyroidism: Is it time for individualized molecular-based surgery?

Mizamtsidi Maria , Nastos Konstantinos , Palazzo Fausto , Constantinides Vasilis , Dina Roberto , Farenden Megan , Vassiliou Ioannis , Gazouli Maria

Introduction: Sporadic primary hyperparathyroidism (sporadic PHPT) is a common endocrine disorder, usually caused by a single parathyroid adenoma. However, up to 15% of patients present with multiple gland disease (MGD), which cannot be always diagnosed preoperatively, raising serious management problems. No predictive genetic screening tests are currently available to distinguishing adenomas from MGD in sporadic PHPT. MiRNAs are widely established as genetic molecules that ha...