Searchable abstracts of presentations at key conferences in endocrinology

ea0032s22.3 | Improving diagnosis of primary aldosteronism | ECE2013

Adrenal vein sampling

Mulatero Paolo , Monticone Silvia , Buffolo Fabrizio , Veglio Franco

Primary aldosteronism is the most common form of secondary hypertension. The detection of primary aldosteronism is of particular importance, because it provides an opportunity for a targeted treatment (surgical for unilateral forms and medical with mineralocorticoid receptor antagonists for bilateral forms). PA diagnosis comprises screening, confirmation testing and subtype diagnosis.Guidelines recommend that all patients for whom the surgical treatment ...

ea0037ep370 | Diabetes (pathiophysiology & epitemiology) | ECE2015

Comparison between aldosterone and renin measurement by chemiluminescent immunoassay and RIA for the diagnosis of primary aldosteronism

Burrello Jacopo , Buffolo Fabrizio , Monticone Silvia , Williams Tracy Ann , Viola Andrea , Mengozzi Giulio , Veglio Franco , Mulatero Paolo

Objective: Primary aldosteronism (PA) is the most frequent cause of secondary hypertension. According to the Endocrine Society Guidelines, up to 50% of hypertensive patients should be screened for PA, using the aldosterone to renin (or plasma renin activity (PRA)) ratio (AARR and ARR respectively). The automated Diasorin LIAISON chemiluminescent immunoassay for renin and aldosterone measurement became available and in many laboratories is currently used instead of the classica...

ea0081p9 | Adrenal and Cardiovascular Endocrinology | ECE2022

Development and internal validation of a predictive model for the estimation of pheochromocytoma recurrence risk after radical surgery

Lopez Chiara , Parasiliti Caprino Mirko , Bioletto Fabio , Bollati Martina , Maletta Francesca , Caputo Marina , Gasco Valentina , La Grotta Antonio , Limone Paolo , Borretta Giorgio , Volante Marco , Papotti Mauro , Terzolo Massimo , Morino Mario , Pasini Barbara , Veglio Franco , Ghigo Ezio , Arvat Emanuela , Maccario Mauro

Objective: Various features have been identified as predictors of relapse after complete resection of pheochromocytoma, but a comprehensive multivariable model for recurrence risk prediction is lacking. The aim of this study was to develop and internally validate an integrated predictive model for post-surgical recurrence of pheochromocytoma.Methods: The present research retrospectively enrolled 177 patients affected by pheochromocytoma and submitted to ...

ea0037ep66 | Adrenal cortex | ECE2015

Clinical significance of contralateral adrenal suppression during adrenal vein sampling in primary aldosteronism

Monticone Silvia , Satoh Fumitoshi , Viola Andrea , Fischer Eveline , Vonend Oliver , Bernini Giampaolo , Quinkler Marcus , Giacchetti Gilberta , Morimoto Ryo , Willemberg Holger , Maccario Mauro , Veglio Franco , Ito Sadayoshi , Reincke Martin , Mulatero Paolo

Objective: Adrenal vein sampling (AVS) is recognised by Endocrine Society guidelines as the only reliable mean to distinguish between aldosterone producing adenomas and bilateral adrenal hyperplasia, the two most common subtypes of primary aldosteronism (PA). However, AVS protocols are not standardised and vary between centres. The objective of the present study was to assess whether the presence or absence of contralateral adrenal (CL) suppression has an impact on the postope...