Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp89 | Diabetes & complications 2 | ECE2017

Clinical assessment of trabecular bone microstructure in type 2 diabetes mellitus with Trabecular Bone Score (TBS)

Perez Maria Dolores Aviles , Martin Antonia Garcia , Rodriguez Cristina Novo , Serrano Rafael Nieto , Vela Elena Torres , Torres Manuel Munoz

Introduction: Type 2 diabetes mellitus (T2DM) is a risk factor for osteoporotic fractures although bone mineral density is increased. As such, there is a need for improved approaches to estimate fracture risk in such individuals. The Trabecular Bone Score (TBS) is a new technique to determine the trabecular bone microarchitecture.Objective: Our aim was to evaluate evaluate the usefulness of TBS in T2DM patients.Methods: We compared...

ea0056p509 | Diabetes therapy | ECE2018

Addition of sodium-glucose co-transporter type 2 inhibitors to diabetic patients type 2 in treatment with glucagon-like peptide-1 agonists: clinical results

Laguna Ma del Carmen Serrano , Ponce Maria Hayon , Martinez David Blanquez , Perez Maria Dolores Aviles , Vela Elena Torres

Background: The complex involvement of multiple metabolic defects in the pathogenesis of type 2 diabetes mellitus (T2DM) makes difficult the treatment in monotherapy, therefore, the use of different antidiabetic drugs with different and complementary mechanisms of action could result in better glycemic control with favorable metabolic changes.Objective: To determine the effectiveness and safety of the addition of a sodium-glucose co-transporter type 2 in...

ea0056p907 | Endocrine Disruptors | ECE2018

Cross hormone therapy in transgender individuals: changes in lipid profile and other cardiovascular risk factor

Laguna Ma del Carmen Serrano , Ponce Maria Hayon , Martinez David Blanquez , Perez Maria Dolores Aviles , Vela Elena Torres

Background: Cross-sex hormone therapy (CHT) is known to lead to alterations in cardiovascular risk factor(CVRF).Objective: To assess changes in lipid profile and other CVRF in transsexual subjects receiving CHT.Materials and methods: Retrospective longitudinal study. We evaluated individuals with gender identity disorder following CHT, assisted in the Gender Identity Unit from 2015 to 2017. Primary endpoint was lipid profile change...

ea0063p923 | Diabetes, Obesity and Metabolism 3 | ECE2019

Flash glucose monitoring system in children under 18 years old with diabetes mellitus type 1 in the southern hospital area of Granada: preliminary results

Utrero Sara Leon , Ponce Maria Hayon , Laguna Ma Del Carmen Serrano , Torres Elena Lopez-Mezquita , Charneco Miguel Quesada , Vela Elena Torres

Objective: To evaluate the baseline characteristics and their evolution three months after implantation of the Flash glucose monitoring System (Freestyle Libre), after financing by the Andalusian Health Service in patients under 18 years old with type 1 diabetes mellitus (DM1) in our hospital area.Material and Methods: A descriptive observational and retrospective study that includes patients with DM1 under 18 years old from the southern hospital area of...

ea0063p974 | Diabetes, Obesity and Metabolism 3 | ECE2019

Canagliflozin: Ankle-Brachial index (ABPI) and risk of amputations

Laguna Ma del Carmen Serrano , Ponce Maria Hayon , Utrero Sara Leon , Perez Luisa Sebastian , Torres Enrique Redondo , Charneco Miguel Quesada , Vela Elena Torres

Objectives: Assess the canagliflozin effect on the ABPI in patients without previous treatment with iSGLT-2 as a possible etiology of tissue hypoperfusion and a risk factor for amputations.Material and methods: Prospective observational study where we analyzed patients diagnosed of type 2 diabetes mellitus (DM2) with poor metabolic control and without prior treatment with iSGLT-2, which is initiated treatment with canagliflozin. Clinical, biochemical par...

ea0056gp42 | Adrenal medulla and NETs | ECE2018

Pituitary adenoma and pheochromocytoma/paraganglioma: a multicausal association of tumors

Guerrero Fernando , Fajardo Carmen , Vela Elena Torres , Gimenez-Palop Olga , Gil Arturo Lisbona , Martin Tomas , Gonzalez Natividad , Diez Juan Jose , Iglesias Pedro , Villabona Carles

Background: Pituitary adenomas (PA) and pheochromocytomas/paragangliomas (PCC/PGL) are the main components of MEN1 and MEN2, respectively. Although the presence of both tumors (3P association, 3PAs) in the same patient could be as a result of coincidence, at least in some cases, a common pathogenic mechanism has been involved. Recently has been confirmed that germline mutations in genes coding succinate dehydrogenase (SDH) play a role in pituitary tumorigenesis. Furthermore, M...