Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep651 | Endocrine tumours and neoplasia | ECE2016

Hirsutism with rapid onset presenting in a 62-year-old postmenopausal woman

Tzaves Ioannis , Papadakis Georgios , Moustakas Konstantinos , Keramidas Ioannis , Kaltzidou Victoria , Veniou Eirini , Kalinoglou Nikolaos , Tertipi Athanasia

Introduction: Virilizing tumors are rare, but frequent cause of virilization in postmenopausal women.Case report: A 62-year-old postmenopausal woman presented with a rapid onset of hirsutism with increased terminal hair growth, particular on chin and abdomen, frontal male pattern balding in the last 5 months. Physical examination revealed a low-pitched, deepened voice and clitoromegaly. The Ferriman–Gallwey score was 18. Laboratory evaluation: Testo...

ea0022p445 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

The use of receptor tyrosine kinase inhibitors in metastatic differentiated thyroid carcinoma

Gkountouvas Anastasios , Kostoglou-Athanassiou Ifigenia , Veniou Eirini , Thomas Dimitrios , Aggelopoulou Anastasia , Nikas Marios , Ziras Nicolaos , Kaldrymides Philippos

The management of metastatic differentiated thyroid carcinoma included until recently the use of therapeutic 131I, radiotherapy and in specific cases chemotherapy. However, recently new agents entered in the management of differentiated metastatic thyroid carcinoma which aim at specific cell receptors and inhibit the growth of the carcinoma in a specific and targeted way.The aim was to present the experience of the use of the receptor tyrosine...

ea0022p854 | Thyroid | ECE2010

Differentiated thyroid carcinoma in young adults

Gkountouvas Anastasios , Kostoglou-Athanassiou Ifigenia , Pappas Anastasios , Veniou Eirini , Nikas Marios , Aggelopoulou Anastasia , Thomas Dimitrios , Kaldrymides Philippos

Differentiated thyroid carcinoma represents a small percentage of human carcinomas. However, it is the commonest endocrine neoplasm and if diagnosed and treated properly does not affect the long-term survival of the patients.Aim: The aim was to study differentiated thyroid carcinoma affecting young adults.Patients and methods: All patients presenting with thyroid carcinoma to the department from 01.01.2002 to 31.12.2008 were review...

ea0020p285 | Clinical case reports and clinical reports | ECE2009

Treatment of metastatic medullary thyroid carcinoma with sorafenib

Kaldrymides Philippos , Kostoglou-Athanassiou Ifigenia , Goudouvas Anastasios , Veniou Eirini , Bakola Theodosia , Agelopoulou Anastasia , Thomas Dimitrios , Ziras Nikolaos

Medullary thyroid carcinoma is an uncommon malignancy of hereditary and sporadic presentation. Mutations in the RET-protooncogene are involved in the pathogenesis of >50% of the sporadic cases. Currently, there is no effective treatment for metastatic medullary thyroid carcinoma. The aim was to present a case of metastatic medullary thyroid carcinoma that was treated by the administration of sorafenib, a multiple kinase inhibitor.A patient, female ag...

ea0016p814 | Thyroid | ECE2008

Mixed papillary, poorly differentiated and anaplastic thyroid carcinoma

Kostoglou-Athanassiou Ifigenia , Goudouvas Anastasios , Thomas Dimitrios , Bakola Theodosia , Veniou Eirini , Batika Pelagia , Athanassiou Panagiotis , Kaldrymidis Philippos

Well differentiated thyroid carcinoma is associated with prolonged survival in terms of decades and anaplastic carcinoma is associated with survival in months. Intermediate malignancy with a more guarded prognosis is also known to exist.The aim was to describe the case of a patient with a mixed papillary, poorly differentiated and anaplastic thyroid carcinoma.A female patient, aged 73 years presented with a multinodular goiter and ...

ea0056p632 | Clinical case reports - Thyroid/Others | ECE2018

Patient with neurofibromatosis type 1 and follicular thyroid cancer

Kanouta Fotini , Kalaitzidou Styliani , Triantafillou Eleni , Drousou Aspasia , Kyrimis Taxiarchis , Tampouratzi Dimitra , Kotis Michalis , Papadakis Georgios , Kaltzidou Victoria , Veniou Eirini , Drakopoulou Anna , Karavasili Chrysa , Mastorakos Georgios , Tertipi Athanasia

Objectives: Neurofibromatosis type 1 (NF1) is an autosomal, dominant, genetic disorder. The genetic lesion in neurofibromatosis type 1 is located at locus 17q11.2 that harbors the neurofibromin gene. Patients have 3-4 times higher possibility to develop malignancies relative to the general population. The endocrine manifestations of neurofibromatosis include precocious puberty, short stature, osteoporosis and pheochromocytoma. We present a patient with neurofibromatosis type 1...

ea0056p1120 | Thyroid cancer | ECE2018

Thyroid ultrasonographic characteristics and Bethesda results after FNAB

Kanouta Fotini , Triantafillou Eleni , Papadakis Georgios , Kalaitzidou Styliani , Drosou Aspasia , Sapera Aggeliki , Tampouratzi Dimitra , Kotis Michalis , Kyrimis Taxiarchis , Drakopoulou Anna , Kaltzidou Victoria , Veniou Eirini , Karavasili Chrysa , Plyta Styliani , Tertipi Athanasia

Objectives: Fine needle aspiration biopsy (FNAB) is the initial investigation of choice for thyroid nodules. The Bethesda System (B) classifies thyroid cytological patterns into six categories (B1-6) according to risk for malignancy.Methods: A total of 1113 patients (210 males/903 females) underwent FNAB for the same number of thyroid nodules. Their mean age was 56.2±21.6 years±S.D. We correlated the demographic profile (age and ...

ea0056ep2 | Adrenal and Neuroendocrine Tumours | ECE2018

Gastric NET due to atrophic gastritic combined with multiglandular syndrom type 3

Tampouratzi Dimitra , Papatheodorou Konstantinos , Tzaida Olga , Sapera Aggeliki , Kalaitzidou Styliani , Drosou Aspasia , Kanouta Fotini , Triantafillou Eleni , Kotis Michalis , Kyrimis Taxiarchis , Papapdakis Georgios , Drakopoulou Anna , Kaltzidou Victoria , Veniou Eirini , Karavasili Chrysa , Vecchini Ginno , Tertipi Athanasia , Nikolakis Dimitrios

Introduction: Neuroendocrine tumors (NETs) are neoplasms that arise from cells of the endocrine and nervous systems. They most commonly occur in the intestine and are graded histologically according to markers of cellular proliferation. G1 and G2 neuroendocrine neoplasms are called neuroendocrine tumors (NETs) – formerly called carcinoid tumors. G3 neoplasms are called neuroendocrine carcinomas (NECs).Objectives: We present a case of a patient with ...

ea0056ep179 | Thyroid | ECE2018

Prognostic factors affecting neck lymphnode recurrence and distant metastasis in papillary thyroid cancer: results of a study in 40 patients

Papadakis Georgios , Triantafillou Eleni , Kanouta Fotini , Drosou Aspasia , Kalaitzidou Styliani , Sapera Aggeliki , Tampouratzi Dimitra , Kotis Michalis , Kyrimis Taxiarchis , Aravantinou Aggeliki , Karavasili Chrysa , Drakopoulou Anna , Veniou Eirini , Kaltzidou Victoria , Tertipi Athanasia

Objectives: Overall, papillary and follicular carcinoma is associated with a 30-year cancer-related death rate of 6 and 15%, respectively. Poorer outcomes have been associated with older age, male gender, tumor size, grade and extrathyroidal extension. We investigated the clinical and laboratory characteristics of 40 patients who presented recurrence of thyroid disease.Patients data: • 40 Patients (21 Females and 19 males) with papillary thyroid can...