Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep1182 | Late Breaking | ECE2022

Association between lipid profile and diabetic nephropathy in type 1 diabetes mellitus

Poskaite Patricija , Radzeviciene Lina , Verkauskiene Rasa

Introduction: Diabetic nephropathy (DN) is a severe complication of type 1 diabetes mellitus (T1DM) and has become common primary disease leading to end-stage renal disease worldwide. Abnormalities in lipid metabolism is very important in the progression of renal damage in patients with T1DM.Aim: to assess the relationship between lipid abnormalities and diabetic nephropathy in type 1 diabetes mellitus patients. Methods: we perform...

ea0063gp246 | Disturbances of Reproduction | ECE2019

Is monosomia related to poorer cardiometabolic state in Turner syndrome?

Kriksciuniene Ruta , Zilaitiene Birute , Lukosevicius Saulius , Verkauskiene Rasa

Introduction: 45,X karyotype is known to be related to more severe phenotype disorders, still comparative analysis of the karyotypes and phenotypes in Turner syndrome (TS) is difficult, even in the largest studies, mainly due to differences in patient‘s age and variability in the definition of clinical features (1). We aimed: to assess if monosomia in Turner syndrome patients is related to their cardiometabolic features.Methods: 75 females with conf...

ea0049ep434 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

The importance of islet antigen-2 and glutamic acid decarboxylase antibodies in proper diagnosis of diabetes mellitus at the age ≥30 and <70 years

Kondrotiene Aiste , Danyte Evalda , Zalinkevicius Rimantas , Verkauskiene Rasa

Objective: Misclassification of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) is quite common and crucial to choice of appropriate therapy. The aim of the study was to evaluate the correspondence of islet antigen-2 (Anti IA2) and glutamic acid decarboxylase (Anti GAD65) antibodies with clinical diagnosis.Methods: The Anti IA2 and Anti GAD65 were measured in 583 patients (337 males and 246 females) diagnosed with T1DM or T2DM with not typical manifest...

ea0049ep542 | Diabetes complications | ECE2017

Emotional state association with microvascular complications, disease duration and glycaemic control in type 1 diabetic patients

Prakapiene Edita , Zukas Karolis , Radzeviciene Lina , Verkauskiene Rasa

The aim: Of the study was to determine the relationship between depression and anxiety symptoms and chronic diabetes complications, disease duration, glycaemic control in type 1 diabetic patients.Methods: 18–54 year old 215 patients with T1DM were enrolled in the study. Participants filled questionnaires about DM, disease duration, complications and Beck’s depression (DB) and anxiety (BA) inventory. All patients were evaluated for microvascular...

ea0049ep1102 | Female Reproduction | ECE2017

The relation between sex hormones and sexual function in women with Turner syndrome

Kriksciuniene Ruta , Zilaitiene Birute , Sematonyte Justina , Verkauskiene Rasa

Objectives: To evaluate sexual function in women with Turner syndrome (TS) in the relation with sex hormones.Methods: The study was undertaken in Lithuanian University of Health Sciences. 65 women with genetically confirmed TS (18–45 years) were enrolled and compared with 65 age-matched healthy controls. Sexual function was evaluated using The Female Sexual Function Index (FSFI). Risk for sexual dysfunction was defined as FSFI score ≤ 26.55. B...

ea0041ep124 | Bone &amp; Osteoporosis | ECE2016

Bone mineralization and hormonal status in Turner syndrome patients: cross sectional one population study

Klimaite Raimonda , Kriksciuniene Ruta , Zilaitiene Birute , Verkauskiene Rasa

Introduction: Women with Turner syndrome (TS) are known to be at risk of decreased BMD (dBMD). Sex hormone replacement therapy is crucial to ensure the proper BMD formation, although the dBMD remains a problem in TS.Aim: To investigate the prevalence of decreased bone mineralization and it’s association with hormone levels in TS.Subjects: Women with geneticaly confirmed TS aged ≥ 18 year.Methods: T...

ea0041ep227 | Cardiovascular Endocrinology and Lipid Metabolism | ECE2016

Higher than expected prevalence of the aortic dilation in Turner syndrome in Lithuanian population

Kriksciuniene Ruta , Zilaitiene Birute , Ereminiene Egle , Verkauskiene Rasa

Introduction: Aortic dilation (AD) is the life threating complication of Turner syndrome (TS). The reported prevalence of AD in TS various between 12 and 39%. Factors predicting enlargement of diameter of aorta (DA) are still under investigation.Aim: To assess the prevalence of AD in TS in Lithuanian population, to evaluate the possible predictors of AD development.Methods: Forty-three patients with TS aged ≥18 year were enro...

ea0041ep269 | Clinical case reports - Pituitary/Adrenal | ECE2016

Pregnancy in patient with GH secreting pituitary adenoma: a case report

Knispelis Robertas , Lebedevaite Kristina , Lasiene Jurate , Zilaitiene Birute , Verkauskiene Rasa

Introduction: GH producing pituitary adenomas are associated with infertility. Hereby the first case in Lithuania, when acromegaly patient got pregnant and delivered is reported.Case presentation: 33-year-old woman visited endocrinologist complaining of secondary amenorrhoea. Due to elevated prolactin – 3016 mU/l (NR<418), bromcriptine treatment was started. The patient discontinued treatment after three months because of restoration of regular ...

ea0035p166 | Calcium and Vitamin D metabolism | ECE2014

Do Lithuanian military conscripts suffer from hypovitaminosis D?

Preiksa Romualdas Tomas , Gailyte Ieva , Lasaite Lina , Verkauskiene Rasa

The aim of the study was to evaluate vitamin D levels in Lithuanian male military conscripts and its association with PTH, osteocalcin and testosterone, body muscles and LBM percentage, as well as depression–sadness, tension–anxiety and psychological and physical quality of life.Methods: A total of 262 healthy Lithuanian male military conscripts were tested for vitamin D, PTH, osteocalcin and testosterone concentration and 155 (59.2%) of them w...

ea0035p813 | Paediatric endocrinology | ECE2014

Polycystic ovary syndrome in overweight and obese adolescent girls and its association with insulin resistance and metabolic syndrome

Smetanina Natalija , Valickas Raimondas , Seibokaite Audrone , Verkauskiene Rasa

Background: The prevalence of polycystic ovary syndrome (PCOS) in adolescents is reported up to 38.9%. Obesity is a known risk factor associated with PCOS increasing the risk of metabolic syndrome (MS). Up to 25% of adolescents with PCOS may have derangements in glucose metabolism and insulin resistance (IR).Aim: To evaluate PCOS prevalence in overweight/obese adolescent girls and to assess the association with BMI, MS and IR.Metho...