Endocrine Abstracts

Background and aims: The aim of this study was to assess the effects of docosahexaenoic (DHA) and eicosapentaenoic acid (EPA) on the heart rate variability (HRV), some biochemical parameters in patients (pts) with Type 2 diabetes mellitus and cardiovascular aunonomic neuropathy (CAN).Materials and methods: 39 pts with CAN (54±5 yrs) were allocated in two groups: A (n=26) were receiving capsules of fish oil every day (2.0 g EPA, 2.0 g DHA and ...

Introduction: The aim of study was to analyse the effect of long-chain polyunsaturated higher ω-3 fatty acids (PUFAs) on the arterial stiffness parameters in patients with type 2 diabetes (T2DM) and cardiovascular autonomic neuropathy (CAN).Description of methods: The study involved 39 patients with moderate CAN (55.2±3.8 years, HbA1c 7.1±0.5%. The aorta (AIxao), brachial augmentation index (AIxbr), pulse wave velocity (PWV) were assessed ...

Background and aims: The present study has examined the effect of α-lipoic acid (ALA) and nicotinamide (NA) on the heart rate variability (HRV), superoxide dismutase (SOD), gluthation peroxidase (GPO), catalase activities, reduced gluthatione (GSH), malondialdegide (MDA) contents in the RBCs’ in Type 2 diabetic patients (T2DM) with cardiovascular autonomic neuropathy (CAN).Materials and methods: 59 patients with T2DM and CAN (59.3±7.9 year...

Background and Aims: The aim of this study was to evaluate the effects of pioglitazone (PGZ) and metformin (MET) plus Hypocaloric Diet (HD) in young patients with obesity and impaired oral glucose-tolerance test (75 g glucose).Materials and methods: 49 patients (17.1±1.2 yrs) were allocated in groups: A (n=14) received PGZ 30 mg tid plus HD, B (n=12) - MET 1000 mg tid plus HD, C - PGZ 30 mg plus MET 1000 mg plus HD (n=11), D (<i...

Background and aims: The aim of this study was to assess the effect of docosahexaenoic (DHA) and eicosapentaenoic acid (EPA) on the heart rate variability (HRV), dynamics of such biochemical parameters in patients (pts) with Type 2 DM and cardiovascular aunonomic neuropathy (CAN).Materials and methods: Forty-nine pts with CAN (54±5 years) were allocated in two groups. Pts of group A (n=17) were receiving capsules of fish oil every day (‘...

Background and aims: The aim of this study was to assess the effects of simvastatin (SIM), eicosapentaenoic (EPA), docosahexaenoic acid (DHA) on dynamics of such biochemical parameters in type 2 diabetic patients with cardiomyopathy (DCMP).Materials and methods: Twenty-five patients with DM and DCMP received SIM 20 mg tid (group A); B (n=37) – capsules of fish oil (‘Epadol’: 2.0 g EPA, 2.0 g DHA and 0.1% α-tocopherol acetate), ...