Searchable abstracts of presentations at key conferences in endocrinology

ea0035p95 | Bone and Osteoporosis | ECE2014

Osteoporosis in young male secondary to cancer treatment: case report

Simoes-Pereira Joana , Silva-Vieira Margarida , Pereira Maria Conceicao

Introduction: Children undergoing treatment for cancer are prone to several long-term endocrine complications, which can permanently affect bone tissue.Case report: A 25-year-old man was diagnosed with right maxillary sinus rhabdomyosarcoma at the age of 5. He was submitted to chemotherapy – intrathecal methotrexate+prednisolone and i.v. vincristine+actinomycin+ifosfamide – and submaxillary+cervical radiotherapy, 60Gy. At the age of 12, he was ...

ea0035p1146 | Thyroid Cancer | ECE2014

Long-term follow-up of young patients submitted to radiotherapy: analysis of ten thyroid cancer cases

Simoes-Pereira Joana , Silva-Vieira Margarida , Pereira Maria Conceicao

Introduction: The increasing risk of thyroid cancer (TC) in patients who underwent radiotherapy is well documented, especially at early ages. In our center, young patients undergoing cancer treatments are referenced to Endocrine Rehabilitation Clinics (ERC). Their risks are initially identified and monitored regularly. We intended to analyze the characteristics and outcomes of patients who developed post-radiotherapy TC.Methods: Medical records of patien...

ea0063ep125 | Reproductive Endocrinology | ECE2019

A rare case of hypergonadotrophic hypogonadism by 47,XXY/46,XX mosaic

Chaves Catarina , Cunha Filipe , Rangel Ricardo , Coelho Daniela , Vieira Margarida , Garrido Susana , Martinho Mariana , Almeida Margarida

Introduction: Klinefelter syndrome (KS) represents the most common cause of hypergonadotrophic hypogonadism, with an estimated prevalence of 1:500 to 1:1000 men. This syndrome is characterized by the presence of an additional X chromosome. Eighty percent present with a 47,XXY karyotype and the remaining 20% present with a 47,XXY/46,XY mosaic or with multiple X chromosome aneuploidies, often with additional Y chromosomes. The presence of a 47,XXY/46,XX mosaic with male phenotyp...

ea0041ep720 | Male Reproduction | ECE2016

Adjustment of testosterone and dihydrotestosterone reference intervals to the male Portuguese population

Simoes-Pereira Joana , Prazeres Susana , Macedo Daniel , Silva-Vieira Margarida , Marques Pedro , Pereira Maria Conceicao

Introduction: In our practice we’ve been following some oncologic survivors patients with low-low/normal levels of testosterone who are asymptomatic. Aims: to determine the levels of total (TT) and free testosterones (FT) and dihydrotestosterone (DHT) in healthy men, in order to find the reference intervals (RI) adjusted to our population and compare them with those provided by the kit-producers (KP).Methods: We collected blood samples from 125 heal...

ea0032p1096 | Thyroid cancer | ECE2013

Radioactive iodine therapy in papillary thyroid carcinomas staged as T1

Marques Pedro , Macedo Daniel , Pereira Joana , Vieira Margarida , Leite Valeriano , Bugalho Maria

Introduction: 131I therapy in patients with papillary thyroid carcinomas (PTC) ≤2 cm and without extrathyroidal extension (T1) depends on multifactorial analysis: age, multifocality, histological criteria, lymph node or systemic metastasis. The study purposes were analyze PTC-T1 and compare the groups treated only with surgery vs combined therapy (surgery and 131I).Methods: Retrospective analysis of clinical files of PTC-T1 pa...

ea0070aep644 | Pituitary and Neuroendocrinology | ECE2020

A case of developmental delay by 18q23 deletion syndrome

Chaves Catarina , Martinho Mariana , Brandão Carla , Rodrigues Catarina , Cunha Filipe , Garrido Susana , Vieira Margarida , Almeida Margarida

Introduction: Monosomy 18q represents a partial deletion of the long arm of chromosome 18, with an estimated prevalence of 1:100 000. This syndrome is characterized by a highly variable phenotype. The symptoms and their severity depend on which part of the chromosome is missing. Most common manifestations are hypotonia, developmental delay, short stature, growth hormone deficiency, hearing loss and external ear anomalies, intellectual disability, palatal defects, dysmorphic fa...

ea0070aep664 | Pituitary and Neuroendocrinology | ECE2020

The role of repeated prolactin samples in patients with hyperprolactinaemia

Rodrigues Catarina , Cunha Filipe , Chaves Catarina , Silva Vieira Margarida , Silva André , Garrido Susana , Martinho Mariana , Almeida Margarida

Introduction: Current guidelines recommend a single prolactin sampling for the diagnosis of hyperprolactinaemia. Nonetheless, in some patients, prolactin levels may normalize in a subsequent sampling or if prolactin is collected through a venous catheter some time after puncture. We aimed to assess the percentage of patients in which prolactin remained elevated in repeated sampling and to determine the best prolactin cutoff associated with persistent hyperprolactinaemia.<p...

ea0081rc1.1 | Rapid Communications 1: Diabetes, Obesity, Metabolism and Nutrition 1 | ECE2022

Predictors of missing postpartum reclassification OGTT in women with gestational diabetes

Cidade-Rodrigues Catarina , Cunha Filipe , Chaves Catarina , Pereira Catarina , Paredes Silvia , Vieira Margarida , Melo Anabela , Figueiredo Odete , Morgado Ana , Martinho Mariana , Almeida M. Ceu , Almeida Margarida

Introduction: Women with gestational diabetes (GD) have an increased risk of developing future type 2 diabetes mellitus (T2DM). A reclassification oral glucose tolerance test (OGTT) is currently recomended in the postpartum period. However, most studies report a compliance rate below 50% and as low as 23%.Objectives: We aimed to study predictors of missing postpartum OGTT in women with GD.Materials and Methods: Retrospecti...