Endocrine Abstracts

Objectives: Congenital adrenal hyperplasia (CAH) is a rare condition caused by enzyme deficiency in cortisol biosynthesis. Patients with CAH require lifelong therapy, with the aim of replacing deficient hormones (cortisol +/− aldosterone) and reducing excess androgen production. Guidelines state that the lowest effective glucocorticoid (GC dose) should be used; however, current GC therapy is suboptimal, and supraphysiological GC doses are used to reduce excess androgens....

The number of the people with type 2 diabetes is increasing globally, therefore there is an increasing need to identify diabetes earlier and more efficiently. Nearly 80% of people with diabetes live in low and middle income countries (LMICs). Traditionally, we have relied on glucose-based criteria (fasting, postprandial, and random) to make the diagnosis of diabetes; however, HbA1c has recently been endorsed as a diagnostic test, as superior alternative to glucose-based criter...

Introduction: Subclinical hypothyroidism (SCH) can impair concentration and memory skills. If this is a case among adolescents it may impair learning abilities, which in turn may be the cause of poorer performance on various tests and exams. Therefore, the aim of this study was to evaluate the prevalence of SCH in teenage girls attending the gymnasia in the city of Starogard Gdański.Material and methods: In total 487 girls (age range 11.5–14.7 ...