Searchable abstracts of presentations at key conferences in endocrinology

ea0011p612 | Neuroendocrinology and behaviour | ECE2006

Positive correlation between AcroQol and SF-36 and negative with BDI in sample of 60 acromegalics

Abreu M , Carvalho D , Vinha E , Webb S , Medina JL

Quality of Life (QoL) is a very important issue in the management of a chronic disease like acromegaly. Recently the AcroQol questionnaire was developed to evaluate the QoL in different acromegalic populations. We decided to compare the scores of AcroQol and 2 other different questionnaires: one related to general well-being (SF-36) and the other to evaluate depression (BDI). We preformed a cross-sectional evaluation of a sample of 60 Portuguese acromegalics, 20 men and 40 wom...

ea0029p396 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Central diabetes insipidus: about two clinical cases

Nogueira C. , Matos M. , Esteves C. , Jorge G. , Couto J. , Neves C. , Queiros J. , Vinha E. , Bernardes I. , Carvalho D.

Introduction: Central diabetes insipidus (CDI) is produced by the destruction of the magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei which results in decreased arginine vasopressin (AVP) synthesis and secretion.Case report 1: Forty-five year old female, previously healthy, was observed in April 2011 complaining of polydipsia, polyuria, nocturia and weight loss since January. Diabetes mellitus (DM) was excluded and she was ...

ea0016p153 | Clinical cases | ECE2008

Hypoglycaemia following gastric banding

Oliveira A , Freitas P , Matos M , Vinha E , Braga D , Maia J , Bartosch C , Exposito M , Medina J

Introduction: Recently, noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS) has been described following Roux-en-Y Gastric Bypass Surgery in morbidly obese patients. It has been proposed that hypoglycaemia might be a consequence of a failure to adaptively decrease insulin secretion after surgery. The authors present a case of a morbidly obese patient with severe hypoglycaemias beginning 3 months after gastric banding surgery.Case report: A 60-ye...

ea0011p170 | Clinical case reports | ECE2006

Cushing’s syndrome due to medullary thyroid carcinoma – a case report

Sousa A , Rodrigues E , Varela A , Vinha E , Braga D , Couto P , Lopes J , Cardoso-Oliveira M , Medina JL

Ectopic ACTH secretion due to malignant tumours is a rare cause of hypercortisolism. Induced metabolic disturbances are often serious and the management of such patients may be difficult. We report the case of a 50-yr-old man who had a sporadic medullary thyroid carcinoma (MTC) removed 2 years ago (Dec/2003). Calcitonin and CEA levels remained high postoperatively and a CT scan revealed liver metastases. In August 2005 he was referred to Endocrinology with symptoms of muscular...

ea0029p379 | Clinical case reports - Pituitary/Adrenal | ICEECE2012

Acromegaly, primary hyperparathyroidism and renal cell carcinoma

Nogueira C. , Vinha E. , Mesquita J. , Belo S. , Capela J. , Pereira J. , Coutinho H. , Castro L. , Souto-Moura C. , Resende A. , Bernardes I. , Carvalho D.

Introduction: Acromegaly is a rare disorder and sporadic cases are the most frequent. It can also occur in association with genetic syndromes, such as Carney complex, multiple endocrine neoplasia type 1 (MEN-1), MEN-1 like syndrome, isolated familial acromegaly and familial isolated pituitary adenomas.Case report: Thirty five -year-old man was observed in 1994 for gynecomastia. Acromegaly was diagnosed based on clinical, biochemical (IGF1 1094.7 ng/ml, b...

ea0026p699 | Diabetes complications | ECE2011

Gilbert syndrome and diabetes: a perfect union?

Matos M J , Souto S B , Oliveira A I , Silva S , Vinha E , Freitas P , Queiros J , Braga D C , Carvalho D

Introduction: Gilbert syndrome is one of the most common inherited diseases, with a prevalence of 5–7%. It is caused by a mutation in UGT1A1 gene, which is in turn responsible for a deficiency in bilirubin glucuronidation. It courses with unconjugated hyperbilirubinemia, and jaundice may occur in adolescence, after fasting, exercise, or in menses, and also with certain drugs. Individuals with Gilbert syndrome seem to have a reduction in the prevalence of micro- and macrov...