Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep62 | Adrenal cortex (to include Cushing's) | ECE2017

Effect of GH treatment on coagulation and fibrinolysis parameters in prepubertal children with growth hormone deficiency

Karachaliou Feneli , Kafetzi Maria , Drakopoulou Maria , Vlachopapadopoulou Elpis , Leka-Emiris Sofia , Fotinou Aspasia , Michalakos Stefanos

Background: Increased fibrinogen levels have been reported in prepubertal children and adolescents with growth hormone deficiency (GHD), which were reduced after rhGH treatment. rhGH treatment has also been shown to exert a beneficial effect on the amount of aPAI-1 in children with GHD.Aim: Of the study was to evaluate whether prepubertal GH deficient (GHD) children showed any impairment in coagulation- and fibrinolysis-related parameters and the effect ...

ea0041ep837 | Obesity | ECE2016

Metabolic syndrome and insulin resistance: can they be predicted by clinical indicators in obese prepubertal children?

Vlachopapadopoulou Elpis , Dikaiakou Eirini , Petrou Vasilis , Anagnostou Elli , Karachaliou Feneli , Patinioti Ioanna , Fotinou Aspasia , Michalacos Stefanos

Aim: To evaluate whether anthropometric indices and acanthosis nigricans can be useful markers for early detection of Insulin Resistance and Metabolic Syndrome (MetS) in overweight and obese children.Methods: Data from 510 prepubertal children (40% boys), 12.9% overweight and 87.1% obese with mean age 9.7±2.5 years were analyzed. Logistic regression analysis was used to investigate which factors were associated with HOMA-IR >3 and metabolic synd...

ea0016p593 | Paediatric endocrinology | ECE2008

Final height and timing of menarche after treatment for idiopathic central precocious puberty (CPP)

Vlachopapadopoulou Elpis , Thomas Dimitrios , Karachaliou Feneli , Vakaki Marina , Kaldrymidis Philipos , Michalacos Stefanos

In true precocious puberty, the increased gonadal steroid secretion increases height velocity, somatic and psychosocial development, and the rate of skeletal maturation and can lead to short adult height. The aim is to assess the impact of suppression therapy of CPP with triptorelin on final adult height and the timing of menarche and pattern of menstrual cycle post-treatment.Materials and methods: Nineteen girls, with CPP, which had completed at least t...

ea0014p184 | (1) | ECE2007

Factors affecting height velocity (HV) during GnRH analog therapy in girls with central precocious puberty (CPP)

Thomas Dimitrios , Vlachopapadopoulou Elpis , Karachaliou Feneli , Vourliotaki Eirini , Kaldrimides Philippos , Michalakos Stefanos

Aim: To assess factors affecting HV during triptorelin suppression treatment for CPP.Materials and methods: Forty-six girls with CPP, with mean age at diagnosis 8.4 yrs who presented with signs and symptoms of puberty before the age of 8 years and were treated with triptorelin for at least 2 years, were studied. All girls were categorized into three groups according to the difference between bone age (BA) and chronological age (ΔBA-CA): group I with...

ea0073pep3.6 | Presented ePosters 3: Pituitary and Neuroendocrinology | ECE2021

Comparative study of growth hormone stimulation levels in growth hormone deficient children vs children with idiopathic short stature

Sofia Leka-Emiri , Athanasouli Fani , Tampouratzi Dimitra , Kafetzi Maria , Dikaiakou Eirini , Petrou Vasilios , Vlachopapadopoulou Elpis , Michalakos Stefanos

IntroductionShort stature (SS) assessment includes the documentation of growth hormone (GH) secretion via GH stimulation tests.ObjectivesTo study retrospectively GH stimulation test results among Greek children with SS and investigate differences among GH deficient (GHD) children vs idiopathic short stature (ISS).MethodsData were collected retrospectively from 190...

ea0032p815 | Paediatric endocrinology | ECE2013

Growth disorders in Greece: baseline data from a multicentre observational study (GENESIS)

Aloumanis Kyriakos , Karachaliou Feneli , Vlachopapadopoulou Elpis , Michalacos Stephanos , Papathanasiou Asteroula , Chrysis Dionysis , Stamoyannou Lela , Karis Christos , Spiliotis Bessie , Drossinos Vangelis , Chrousos George

Aim: The Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS) is an open-label multinational observational study which collects information on management, clinical outcomes and treatment safety of children with growth disorders. Here we present descriptive data from the Greek cohort.Methods and results: In Greece, 211 children (44.5% females, 136 naive to GH treatment at study entry and 18 not GH-treated) have been enrolled, aft...