Searchable abstracts of presentations at key conferences in endocrinology

ea0022p857 | Thyroid | ECE2010

A study of thyroid disorders in pregnancy

Voican Adela , Pavel Oana , Vasile Ionut , Cerga Areta , Bistriceanu Marian

Background and aims: Thyroid disorders (TDs) are frequent in women of reproductive age, with a major influence on both female reproductive function and fetal development. During pregnancy, TDs associate a high risk of miscarriages, premature birth or neonatal morbidity. Our study aimed to assess both TDs prevalence in pregnant women and the need to adjust the necessary treatment during pregnancies complicated with TDs.Patients and method: This is a retro...

ea0022p497 | Female reproduction | ECE2010

The value of ovarian reserve markers in assisted reproductive technology

Voican Adela , Niculescu Gabriela , Manolea Magdalena , Iliescu Dominic , Gheta Carmen , Novac Liliana

Background and aims: Ovarian reserve screening is considered to play a key role in the prediction of quantitative and qualitative aspects in assisted reproductive technologies (ART). The ovarian reserve markers currently used include the serum levels of FSH, oestadiol, inhibin B, anti-Müllerian hormone (AMH) as well as ultrasound antral follicular counts (AFC). Despite controversial results, most of the existing studies suggest that, compared to other markers of the ovari...

ea0081p63 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Exceptional genetic transmission of a ABCC8 mutation in two cases of diffuse hyperinsulinism in a dichorionic diamniotic (DCDA) twin pregnancy

Telehuz Daniela , Oana Plesa , Florence Bouilloud , Adela Voican , Isabela Banu , Jean-Baptiste Arnoux , Helene Wucher , Olivier Dupuy

We present the case of a 36-year-old female with a focal neonatal hyperinsulinism diagnosed at birth in a context of hypoglycemia that was resistant to Diazoxide treatment. A subtotal pancreatectomy was performed and histology showed a focal hyperinsulinism. The mutation of ABCC8 was not searched at this point. The patient developed an insulin dependent diabetes at the age of 9 and required an insulin pump. In 2017 the patient was planning a pregnancy so she consulted a geneti...