Searchable abstracts of presentations at key conferences in endocrinology

ea0016p724 | Thyroid | ECE2008

Subclinical hyperthyroidism and insulin resistance in women with simple goiter

Tzioras Constantinos , Vryonidou Andromachi , Phenekos Constantinos

Introduction: Thyrotoxicosis has been shown to cause deterioration of glucose levels in patients with DM 2 while return to euthyroidism results in better glycaemic control. Studies in normal subjects suggest that increased thyroid hormones may aggravate insulin resistance and decrease pancreatic secretion of insulin but the exact underlying mechanisms have not been completely elucidated. The purpose of this study was to investigate if this also occurs in subclinical hyperthyro...

ea0049ep423 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

High incidence of glucose metabolism disorders in patients undergoing coronary angiography without history of diabetes

Paschou Stavroula A , Kiokas Sotirios , Avdikos Grigorios , Lazaris Efstathios , Vryonidou Andromachi

Introduction: The aim of this study was to investigate the incidence of glycemic disorders in patients undergoing coronary angiography with no prediagnosed type 2 diabetes (T2D), as well as the association of the glycemic status with the extent of the coronary artery disease (CAD).Patients and methods: We studied 170 consecutive patients (134M/36W), 63.9±13.1 (23–95) years old, with not known T2D, who underwent coronary angiography. HbA1c was m...

ea0032p938 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Pituitary apoplexy in clinically nonfunctioning pituitary adenomas: experience of a single center

Karagiannis Apostolos , Boufas Dimitrios , Tzioras Konstantinos , Seretis Andreas , Vryonidou Andromachi

Introduction: Generously supported by IPSEN)-->Clinically nonfunctioning pituitary adenomas (CNFPA) represent 25–50% of all pituitary lesions. They may be asymptomatic and discovered incidentally or they may be diagnosed due to visual impairment or symptoms of pituitary hormone insufficiency. There is little data on apoplexy frequency in the CNFPA.The aim of our study was to assess the frequency of CNFPA a...

ea0049ep1139 | Female Reproduction | ECE2017

Diagnostic performance of non-invasive markers for the presence of nonalcoholic fatty liver disease in premenopausal women with and without polycystic ovary syndrome

Vassilatou Evangeline , Lafoyianni Sophia , Vassiliadi Dimitra-Argyro , Ioannidis Dimitrios , Paschou Stavroula , Mizamtzidi Maria , Vryonidou Andromachi

Introduction: Several markers based on anthropometric and biochemical parameters like fatty liver index (FLI), lipid accumulation product (LAP) index and visceral adiposity index (VAI), have been proposed for the detection of nonalcoholic fatty liver disease (NAFLD).Objective: To evaluate the diagnostic performance of FLI, LAP and VAI as markers of NAFLD in premenopausal women with and without polycystic ovary syndrome (PCOS), assessed for hepatic steato...

ea0041ep785 | Obesity | ECE2016

Interventional changes of thyroid hormone levels do not affect circulating irisin levels in humans

Panagiotou Grigorios , Pazaitou-Panayiotou Kalliopi , Komninou Despina , Paschou Stavroula A. , Kalogeris Nikolaos , Vryonidou Andromachi , Mantzoros Christos S.

Introduction: Thyroid hormones and irisin increase energy expenditure and induce browning of adipose tissue. However, little is known about irisin physiology and regulation. Here we aim to elucidate whether thyroid hormones alter circulating irisin concentrations in humans.Design and subjects: One cross-sectional (case-control) evaluation and two interventions were performed independently from each other, including previously thyroidectomized patients. C...

ea0037ep18 | Adrenal cortex | ECE2015

Subclinical Cushing's syndrome and clinical implications in bilateral compared to unilateral adrenal incidentalomas: a meta-analysis

Paschou Stavroula A , Kandaraki Eleni , Dimitropoulou Fotini , Goulis Dimitrios G , Vryonidou Andromachi

Introduction: The aim of this study was to systematically review the literature for studies that have investigated possible differences in prevalence of subclinical Cushing’s syndrome (SCS) and related clinical implications between patients with unilateral (UAI) and bilateral adrenal incidentalomas (BAI) and to meta-analyze the best evidence available.Methods: Electronic databases PubMed, MEDLINE and EMBASE were systematically searched. Main study o...

ea0037ep1045 | Thyroid (non-cancer) | ECE2015

The effect of anti-TNF therapy on thyroid function in patients with inflammatory bowel disease

Paschou Stavroula A , Kothonas Fotios , Myroforidis Alexandros , Loi Vasiliki , Karayianni Olympia , Poulou Androniki , Goumas Konstantinos , Vryonidou Andromachi

Introduction: Inflammatory bowel disease (IBD) has been associated with various disorders of thyroid function. Many of these patients are now treated with biological agents targeting on TNF-a.Aim: To investigate thyroid function in patients with IBD and the potential effect of anti-TNF therapy.Patients and methods: We studied 41 patients with IBD (25M/16F, 36.4±11 years), without any known thyroid disorder. Eighteen patients (...

ea0035p629 | Female reproduction | ECE2014

Birth weight is associated with important clinical and biochemical parameters of PCOS

Paschou Stavroula A. , Ioannidis Dimitrios , Vassilatou Evangeline , Panagou Maria , Lilis Dimitrios , Tzavara Ioanna , Vryonidou Andromachi

Introduction: Several studies have demonstrated associations of birth weight with metabolic and reproductive abnormalities in adults. The aim of this study was to investigate the birth weight in women with PCOS and its correlation with important clinical and biochemical parameters of the syndrome.Patients and methods: We studied 288 women with PCOS according to the NIH criteria (1990) and 166 women with normal cycles and without clinical or biochemical h...

ea0032p78 | Bone and Osteoporosis | ECE2013

Effects of Denosumab treatment on insulin resistance in postmenopausal women with osteoporosis

Tzioras Konstantinos , Mizamtsidi Maria , Chronaiou Aikaterini , Vasiliou Georgia , Tagara Sofia , Vryonidou Andromachi

Introduction: Denosumab is a new pharmacotherapy option for postmenopausal osteoporosis. It is a human monoclonal antibody against RANKL, acting as an osteoprotegerin (OPG) analog. Recently, osteoprotegerin levels were found to be elevated in type two diabetes while insulin resistance was shown to be positively associated with decreased serum OPG levels, in healthy obese subjects. However, no study has been conducted in order to clarify the effect of anti-RANKL factors adminis...

ea0022p42 | Adrenal | ECE2010

Increased prevalence of metabolic syndrome in patients with subclinical autonomous cortisol hypersecretion by adrenal incidentalomas

Vryonidou Andromachi , Ioannidis Dimitrios , Vassilatou Evangelina , Katsoulis Kostas , Panagou Maria , Panayiotopoulos Kostas , Michalopoulou Stamatina , Tzavara Ioanna

Background: Subclinical autonomous cortisol hypersecretion is the most common hormonal abnormality in patients with adrenal incidentalomas, which is characterized by subtle abnormalities of the hypothalamic–pituitary–adrenal axis (HPA) due to adrenal autonomy. Possible detrimental effects of subclinical hypercortisolism in these patients are still under investigation.Objective: To investigate the prevalence of the metabolic syndrome (MS) in pat...