Searchable abstracts of presentations at key conferences in endocrinology

ea0022p810 | Thyroid | ECE2010

Atorvastatin inhibited proliferation in papillary thyroid cancer cell line

Gulcelik Nese Ersoz , Zeybek Dilara , Kaymaz Figen , Sarisozen Can , Asan Esin , Vural Imran , Usman Aydan

Aim: The role of statins on thyroid cell proliferation is of clinical interest. In this study, we investigated the effect of atorvastatin on papillary thyroid cell line (B-CPAP) and normal thyroid (Nthy-ori3-1) cell lines.Materials and methods: In this in vitro study, B-CPAP and Nthy-ori3-1 cell lines were treated with atorvastatin at 12.5, 25, 50, 100, 200 μM concentrations. At 48 and 72 h MTT, electron microscopy and immunohistochemistry we...