Endocrine Abstracts

A 43-year-old lady with no significant PMH presented with recent onset of polyuria and polydypsia shortly after commencing an SSRI. Cranial diabetes insipidus was diagnosed on water deprivation test and good clinical response to DDAVP was seen. Anterior pituitary function was normal though prolactin elevated. MRI demonstrated a 4 mm enhancing lesion in the hypothalamus in association with a bright pituitary stalk. CXR was normal, ESR and serum ACE negative. The differential di...

We present the case of a 70 year-old man who presented with several months history of tiredness and lethargy. He had a past medical history of ischaemic heart disease. Examination identified a bitemporal hemianopia. Initial investigations demonstrated hyponatraemia, sodium 117 mmol/L (Reference range 132–145) with normokalaemia. Further investigations confirmed hypopituitarism: Short Synacthen Test Cortisol at T=0 min, 125 mmol/L, Cortisol at T=30 mins, 277 mmol/L, free T...